Table 2.
Sample collection rate and sample type for first T790M mutation testing by patient background
| n | Samples collected, n (%) | Sample type†, n (%) | No. samples collected, n (%) | |||
|---|---|---|---|---|---|---|
| Tissue | Cytology | Plasma | ||||
| Overall | 236 | 205 (86.9) | 41 (17.4) | 27 (11.4) | 137 (58.1) | 31 (13.1) |
| Sex | ||||||
| Male | 77 | 67 (87.0) | 18 (23.4) | 10 (13.0) | 39 (50.6) | 10 (13.0) |
| Female | 159 | 138 (86.8) | 23 (14.5) | 17 (10.7) | 98 (61.6) | 21 (13.2) |
| Age at PD, years | ||||||
| < 65 | 43 | 38 (88.4) | 11 (25.6) | 5 (11.6) | 22 (51.2) | 5 (11.6) |
| 65 to < 75 | 91 | 80 (87.9) | 10 (11.0) | 15 (16.5) | 55 (60.4) | 11 (12.1) |
| ≥ 75 | 102 | 87 (85.3) | 20 (19.6) | 7 (6.9) | 60 (58.8) | 15 (14.7) |
| ECOG PS at PD | ||||||
| 0 | 82 | 73 (89.0) | 17 (20.7) | 8 (9.8) | 48 (58.5) | 9 (11.0) |
| 1 | 118 | 105 (89.0) | 19 (16.1) | 15 (12.7) | 71 (60.2) | 13 (11.0) |
| 2 | 27 | 20 (74.1) | 3 (11.1) | 1 (3.7) | 16 (59.3) | 7 (25.9) |
| 3 | 6 | 5 (83.3) | 2 (33.3) | 2 (33.3) | 1 (16.7) | 1 (16.7) |
| 4 | 3 | 2 (66.7) | 0 (0.0) | 1 (33.3) | 1 (33.3) | 1 (33.3) |
ECOG Eastern Cooperative Oncology Group, PD progressive disease, PS performance status
†The denominator used for sample type is the number of patients