Table 3.
Organ residence times (hours) of 11C-UCB-J in humans in comparison with those in non-human primate (NHP). All values displayed as mean ± standard deviation
| Organ | Mean ALL human (n = 4) | Mean ALL NHP (n = 4) | Percent difference (%) |
|---|---|---|---|
| Brain | 0.0733 ± 0.0161 | 0.0729 ± 0.0045 | − 1 |
| Gallbladder | 0.0033 ± 0.0012 | 0.0004 ± 0.0002 | − 88 |
| Heart | 0.0057 ± 0.0009 | 0.0033 ± 0.0013 | − 42 |
| Lower intestine | 0.0216 ± 0.0051 | 0.0073 ± 0.0020 | − 66 |
| Kidneys | 0.0091 ± 0.0008 | 0.0122 ± 0.0023 | 34 |
| Liver | 0.0956 ± 0.0148 | 0.0965 ± 0.0407 | 1 |
| Lungs | 0.0134 ± 0.0063 | 0.0127 ± 0.0061 | − 5 |
| Pancreas | 0.0003 ± 0.0001 | 0.0001 ± 0.0001 | − 66 |
| Spleen | 0.0020 ± 0.0002 | 0.0018 ± 0.0005 | − 10 |
| Stomach | 0.0079 ± 0.0067 | 0.0007 ± 0.0002 | − 91 |
| Urinary bladder | 0.0259 ± 0.0010 | 0.0072 ± 0.0039 | − 72 |
| Remainder | 0.2302 ± 0.0313 | 0.2730 ± 0.0455 | 19 |