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. 2020 Jun 12;12(6):e8580. doi: 10.7759/cureus.8580

Table 1. Summary of various related studies on the significance of an upright T-wave in V1 and TV1 > TV6.

OR: odds ratio; CI: confidence interval

Study Findings
Barthwal et al. [12] TV1 > TV6 sign has sensitivity, specificity, and false positivity of 72.9%, 84.4%, and 15.6% respectively, for significant CAD.
Manno et al. [13] Upright T-wave in V1 was present in 184 of 218 patients who had >75% occlusion of coronary arteries more frequently on the left circumflex artery.
Nalbantgil et al. [14]   TV1 > TV6 had a sensitivity of 16.1%, the specificity of 95.6%, and accuracy of 94.2% for significant coronary artery stenosis.
 Amirzadegan et al. [15] Upright T-wave in V1 > 1.5 mm had OR = 2.38 (1.78 - 3.12) for coronary artery stenosis of greater than 50%.
Stankovic et al. [16] Upright TV1 was an independent predictor of significant CAD (OR 4.249, 95% CI 1.594 - 11.328).