Skip to main content
. 2020 Jul 14;14(7):e0008454. doi: 10.1371/journal.pntd.0008454

Table 1. Diagnostic interpretation of the serology testing results.

Diagnosis Criteria
Confirmed JEV Anti-JEV IgM-positive/equivocal in the S2 and/or S1, and
Anti-JEV PRNT90 titer in S2 ≥4-fold higher from S1, and
Anti-JEV PRNT90 titer in S2 ≥4-fold higher than any DENV titer
Probable JEV Anti-JEV IgM-positive/equivocal in the S2 and/or S1, and
Anti-JEV PRNT90 titer in S2 higher from S1, but
Anti-JEV PRNT90 titer in S2 <4-fold than any anti-DENV titer, and
Anti-DENV IgM-negative in the S1 and S2
DENV Anti-JEV IgM-positive/equivocal in the S2 and/or S1, but
Anti-DENV PRNT90 titer in S2 higher from S1, and
Anti-DENV PRNT90 titer in S2 ≥4-fold higher than JEV titer, and
Anti-DENV IgM-positive in the S1 and/or S2
Flavivirus Anti-JEV IgM-positive/equivocal in the S2 and/or S1, but
Anti-JEV PRNT90 titer in S2 <4-fold than any anti-DENV titer, and
Anti-DENV IgM-positive in the S1 and/or S2

S1, admission serum sample; S2, discharge serum sample; PRNT, plaque reduction neutralization test.