Table 1. Diagnostic interpretation of the serology testing results.
Diagnosis | Criteria |
---|---|
Confirmed JEV | Anti-JEV IgM-positive/equivocal in the S2 and/or S1, and |
Anti-JEV PRNT90 titer in S2 ≥4-fold higher from S1, and | |
Anti-JEV PRNT90 titer in S2 ≥4-fold higher than any DENV titer | |
Probable JEV | Anti-JEV IgM-positive/equivocal in the S2 and/or S1, and |
Anti-JEV PRNT90 titer in S2 higher from S1, but | |
Anti-JEV PRNT90 titer in S2 <4-fold than any anti-DENV titer, and | |
Anti-DENV IgM-negative in the S1 and S2 | |
DENV | Anti-JEV IgM-positive/equivocal in the S2 and/or S1, but |
Anti-DENV PRNT90 titer in S2 higher from S1, and | |
Anti-DENV PRNT90 titer in S2 ≥4-fold higher than JEV titer, and | |
Anti-DENV IgM-positive in the S1 and/or S2 | |
Flavivirus | Anti-JEV IgM-positive/equivocal in the S2 and/or S1, but |
Anti-JEV PRNT90 titer in S2 <4-fold than any anti-DENV titer, and | |
Anti-DENV IgM-positive in the S1 and/or S2 |
S1, admission serum sample; S2, discharge serum sample; PRNT, plaque reduction neutralization test.