Table 1.

Flow Cytometry Analysis of Reactivity of Anti-CEACAM1, Anti-CEACAM5, and NEO-201 mAbs Against Cultured Tumor Cell Lines Derived from Various Types of Solid Tumors

Cell line	CEACAM1+	CEACAM5+/NEO-201+
% positive (MFI)
ASPC-1	61.15 (707)	9.26 (869/9078)
BxPC-3	2.45 (1471)	58.52 (1447/6420)
CFPAC-1	18.67 (1938)	26.95 (1108/1728)
LS174T	2.43 (3287)	26.84 (1030/858)

ASPC-1, BxPC-3, and CFPAC-1 are human pancreatic carcinoma cell lines. LS174T is a human colorectal carcinoma cell line.

The percentage of positive cells and median fluorescence intensity (MFI) values are detailed for each cell line. Positive marker expression appears in bold text, where positivity was defined as % positive >10%.

CEACAM, carcinoembryonic antigen-related cell adhesion molecule; mAb, monoclonal antibody.