Table 2.
Probability of Fertility Preservation Consultation and Procedure for Adolescents and Young Adults Ages 15–39 at Diagnosis from 2008 to 2017
Consultation (n = 2932) |
Procedure (n = 440)a |
|||||
---|---|---|---|---|---|---|
Coefficient | 95% CI | Significanceb | Coefficient | 95% CI | Significanceb | |
Insurance | ||||||
Private | Ref. | Ref. | ||||
Public | −0.0706 | −0.10 to −0.04 | *** | −0.0354 | −0.15 to 0.08 | |
Insured, NOS | 0.0319 | −0.01 to 0.07 | 0.0296 | −0.10 to 0.16 | ||
Uninsured and unknown | −0.0434 | −0.09 to −0.00 | * | 0.0782 | −0.07 to 0.23 | |
Diagnosis | ||||||
Osseous and chondromatous neoplasms and soft tissue sarcomas | Ref. | Ref. | ||||
Leukemia | 0.1392 | 0.06 to 0.22 | ** | −0.0250 | −0.23 to 0.18 | |
Lymphoma | 0.1128 | 0.04 to 0.18 | ** | 0.0039 | −0.18 to 0.19 | |
CNS and other intracranial and intraspinal neoplasms | −0.0678 | −0.12 to −0.01 | * | −0.1095 | −0.33 to 0.11 | |
Germ cell and trophoblastic neoplasms | 0.1232 | 0.04 to 0.20 | ** | 0.3097 | 0.13 to 0.49 | ** |
Melanoma and skin carcinomas | −0.0654 | −0.12 to −0.01 | * | −0.4076 | −0.58 to −0.24 | *** |
Carcinomas | −0.0034 | −0.05 to 0.05 | −0.3570 | −0.52 to −0.20 | *** | |
Misc. specified and unspecified neoplasms | −0.0544 | −0.13 to 0.02 | −0.0936 | −0.41 to 0.23 | ||
Oncologist | ||||||
Nonpediatric | Ref. | Ref. | ||||
Pediatric | 0.0504 | −0.02 to 0.12 | −0.2293 | −0.42 to −0.03 | * | |
RUCA | ||||||
Urban | Ref. | Ref. | ||||
Large rural | −0.0208 | −0.05 to 0.01 | 0.0081 | −0.11 to 0.12 | ||
Small rural | −0.0182 | −0.06 to 0.02 | 0.0016 | −0.13 to 0.13 | ||
Isolated | 0.0151 | −0.03 to 0.06 | 0.0463 | −0.08 to 0.17 | ||
Unknown or international | 0.0263 | −0.18 to 0.23 | −0.4764 | −0.73 to −0.22 | *** | |
Race | ||||||
White | Ref. | Ref. | ||||
Non-White | 0.0139 | −0.04 to 0.06 | 0.0314 | −0.10 to 0.16 | ||
Unknown | 0.0322 | −0.17 to 0.23 | −0.2216 | −0.49 to 0.04 | ||
Ethnicity | ||||||
Non-Hispanic | Ref. | Ref. | ||||
Hispanic | −0.0438 | −0.11 to 0.02 | 0.0196 | −0.26 to 0.30 | ||
Unknown | 0.0052 | −0.17 to 0.18 | 0.2178 | −0.04 to 0.48 | ||
Sex | ||||||
Female | Ref. | c | ||||
Male | 0.0425 | 0.02 to 0.07 | ** | |||
Age at diagnosis (years) | ||||||
15–19 | Ref. | Ref. | ||||
20–24 | −0.0249 | −0.09 to 0.04 | −0.1008 | −0.27 to 0.07 | ||
25–29 | −0.0174 | −0.08 to 0.05 | −0.2312 | −0.39 to −0.07 | ** | |
30–34 | −0.0807 | −0.14 to −0.02 | * | −0.2784 | −0.45 to −0.11 | ** |
35–39 | −0.1194 | −0.18 to −0.06 | *** | −0.2933 | −0.47 to −0.12 | ** |
Year of diagnosis | ||||||
2008 | Ref. | Ref. | ||||
2009 | 0.0138 | −0.04 to 0.06 | −0.2125 | −0.43 to 0.01 | ||
2010 | 0.0230 | −0.03 to 0.07 | −0.1137 | −0.33 to 0.11 | ||
2011 | 0.0424 | −0.01 to 0.10 | −0.2575 | −0.46 to −0.06 | * | |
2012 | 0.0765 | 0.02 to 0.14 | * | −0.2017 | −0.42 to 0.02 | |
2013 | 0.0819 | 0.03 to 0.14 | ** | −0.2719 | −0.48 to −0.06 | * |
2014 | 0.0751 | 0.02 to 0.13 | * | −0.1353 | −0.36 to 0.09 | |
2015 | 0.0789 | 0.02 to 0.14 | ** | −0.0717 | −0.28 to 0.14 | |
2016 | 0.1361 | 0.08 to 0.20 | *** | −0.2080 | −0.40 to −0.02 | * |
2017 | 0.1241 | 0.06 to 0.18 | *** | −0.2457 | −0.44 to −0.06 | * |
Model predicting fertility preservation procedure only includes those who had a consultation.
Significance level corresponds to *p < 0.05, **p < 0.01, and ***p < 0.001.
No female patients underwent any fertility preservation procedure during the study time period; the variable sex was removed from the analyses.
CI, confidence interval.