Table 3.
Probability of Fertility Preservation Consultation and Procedure by Treatment by Pediatric and Nonpediatric Oncologist
Consultation (n = 2932) |
Procedure (n = 440)a |
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---|---|---|---|---|---|---|---|---|---|---|---|---|
Pediatric oncologist (n = 208) |
Nonpediatric oncologist (n = 2724) |
Pediatric oncologist (n = 47) |
Nonpediatric oncologist (n = 393) |
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Coefficient | 95% CI | Significanceb | Coefficient | 95% CI | Significanceb | Coefficient | 95% CI | Significanceb | Coefficient | 95% CI | Significanceb | |
Insurance | ||||||||||||
Private | Ref. | Ref. | Ref. | Ref. | ||||||||
Public | −0.0765 | −0.22 to 0.07 | −0.0684 | −0.10 to −0.04 | *** | −0.0658 | −0.48 to 0.34 | −0.0126 | −0.13 to 0.10 | |||
Insured, NOS | 0.0042 | −0.20 to 0.21 | 0.0329 | −0.01 to 0.08 | −0.2145 | −0.97 to 0.54 | 0.0587 | −0.08 to 0.19 | ||||
Uninsured and unknown | 0.0169 | −0.27 to 0.31 | −0.0407 | −0.08 to 0.00 | 0.3943 | −0.33 to 1.11 | 0.0841 | −0.08 to 0.25 | ||||
Diagnosis | ||||||||||||
Osseous and chondromatous neoplasms and soft tissue sarcomas | Ref. | Ref. | Ref. | Ref. | ||||||||
Leukemia | 0.2199 | −0.03 to 0.47 | 0.1237 | 0.04 to 0.21 | ** | −0.3432 | −0.91 to 0.22 | 0.1517 | −0.18 to 0.48 | |||
Lymphoma | 0.4377 | 0.22 to 0.66 | *** | 0.0625 | −0.01 to 0.13 | −0.0873 | −0.60 to 0.43 | 0.0593 | −0.27 to 0.38 | |||
CNS and other intracranial and intraspinal neoplasms | −0.1492 | −0.33 to 0.04 | −0.0626 | −0.12 to −0.01 | * | −0.5360 | −1.23 to 0.15 | 0.0529 | −0.30 to 0.40 | |||
Germ cell and trophoblastic neoplasms | −0.1649 | −0.67 to 0.34 | 0.1285 | 0.05 to 0.21 | ** | −0.7772 | −1.30 to −0.26 | ** | 0.4335 | 0.12 to 0.75 | ** | |
Melanoma and skin carcinomas | −0.1323 | −0.41 to 0.15 | −0.0674 | −0.13 to −0.01 | * | −0.4950 | −1.15 to 0.16 | −0.2956 | −0.60 to 0.01 | |||
Carcinomas | −0.1399 | −0.34 to 0.06 | −0.0075 | −0.06 to 0.04 | 0.0000 | 0.00 to 0.00 | −0.2654 | −0.56 to 0.03 | ||||
Misc specified and unspecified neoplasms | −0.2555 | −0.43 to −0.08 | ** | −0.0304 | −0.11 to 0.05 | 0.0000 | 0.00 to 0.00 | 0.0000 | 0.00 to 0.00 | |||
RUCA | ||||||||||||
Urban | Ref. | Ref. | Ref. | Ref. | ||||||||
Large rural | −0.1065 | −0.25 to 0.04 | −0.0194 | −0.05 to 0.01 | 0.3161 | −0.35 to 0.99 | −0.0394 | −0.16 to 0.08 | ||||
Small rural | 0.1269 | −0.06 to 0.31 | −0.0261 | −0.06 to 0.01 | −0.3401 | −0.89 to 0.21 | 0.0390 | −0.10 to 0.18 | ||||
Isolated | 0.0855 | −0.09 to 0.26 | 0.0055 | −0.04 to 0.05 | −0.0932 | −0.61 to 0.42 | 0.0622 | −0.07 to 0.19 | ||||
Unknown or international | 0.0373 | −0.16 to 0.23 | −0.4884 | −0.73 to −0.25 | *** | |||||||
Race | ||||||||||||
White | Ref. | Ref. | Ref. | Ref. | ||||||||
Non-White | −0.1469 | −0.33 to 0.04 | 0.0286 | −0.02 to 0.08 | −0.4461 | −1.16 to 0.26 | 0.0580 | −0.07 to 0.19 | ||||
Unknown | 0.0277 | −0.35 to 0.41 | 0.0226 | −0.19 to 0.24 | −0.1854 | −0.44 to 0.07 | ||||||
Ethnicity | ||||||||||||
Non-Hispanic | Ref. | Ref. | Ref. | Ref. | ||||||||
Hispanic | −0.1432 | −0.37 to 0.08 | −0.0290 | −0.09 to 0.04 | 0.3899 | −0.08 to 0.86 | −0.0794 | −0.40 to 0.24 | ||||
Unknown | −0.1374 | −0.36 to 0.08 | 0.0298 | −0.16 to 0.22 | 0.1957 | −0.06 to 0.45 | ||||||
Sex | ||||||||||||
Female | Ref. | Ref. | c | c | ||||||||
Male | 0.1320 | 0.01 to 0.26 | * | 0.0289 | 0.00 to 0.06 | * | ||||||
Age at diagnosis (years) | ||||||||||||
15–19 | Ref. | Ref. | Ref. | Ref. | ||||||||
20–24 | −0.0679 | −0.20 to 0.07 | 0.0108 | −0.07 to 0.09 | 0.3493 | −0.38 to 1.08 | −0.1499 | −0.33 to 0.03 | ||||
25–29 | 0.0416 | −0.13 to 0.21 | 0.0094 | −0.06 to 0.08 | −0.2719 | −0.43 to −0.11 | ** | |||||
30–34 | −0.0582 | −0.13 to 0.01 | −0.3118 | −0.48 to −0.14 | *** | |||||||
35–39 | −0.1572 | −0.51 to 0.20 | −0.0968 | −0.16 to −0.03 | ** | −0.3187 | −0.49 to −0.15 | *** | ||||
Year of diagnosis | ||||||||||||
2008 | Ref. | Ref. | Ref. | Ref. | ||||||||
2009 | 0.0975 | −0.15 to 0.34 | 0.0117 | −0.04 to 0.06 | −0.2126 | −1.16 to 0.73 | −0.2479 | −0.47 to −0.03 | * | |||
2010 | 0.0907 | −0.17 to 0.35 | 0.0172 | −0.03 to 0.07 | −0.1622 | −1.10 to 0.78 | −0.1442 | −0.37 to 0.08 | ||||
2011 | −0.0043 | −0.28 to 0.27 | 0.0462 | −0.01 to 0.10 | −0.4920 | −1.39 to 0.41 | −0.2299 | −0.43 to −0.03 | * | |||
2012 | −0.0194 | −0.26 to 0.22 | 0.0795 | 0.02 to 0.14 | * | −0.2144 | −1.27 to 0.84 | −0.2191 | −0.44 to 0.01 | |||
2013 | 0.1491 | −0.16 to 0.46 | 0.0794 | 0.02 to 0.14 | ** | −0.4834 | −1.74 to 0.78 | −0.2727 | −0.49 to −0.06 | * | ||
2014 | −0.0451 | −0.28 to 0.19 | 0.0870 | 0.03 to 0.15 | ** | −0.0680 | −1.27 to 1.13 | −0.1810 | −0.41 to 0.04 | |||
2015 | 0.1899 | −0.08 to 0.46 | 0.0688 | 0.01 to 0.13 | * | −0.1586 | −1.32 to 1.00 | −0.0944 | −0.30 to 0.11 | |||
2016 | 0.1496 | −0.09 to 0.39 | 0.1358 | 0.07 to 0.20 | *** | −0.4408 | −1.46 to 0.58 | −0.2108 | −0.40 to −0.02 | * | ||
2017 | 0.0384 | −0.20 to 0.28 | 0.1302 | 0.07 to 0.19 | *** | −0.2218 | −1.43 to 0.98 | −0.2610 | −0.45 to −0.07 | ** |
Model predicting fertility preservation procedure only includes those who had a consultation.
Significance level corresponds to *p < 0.05, **p < 0.01, and ***p < 0.001.
No female patients underwent any fertility preservation procedure during the study time period; the variable sex was removed from the analyses.