Table 1. Specific cell surface marker sets for different cell types in adipose tissue.
Cell types | Markers | Fat depots | |
---|---|---|---|
White adipocytes | ASC-1 | S/VAT, S/VAT* | [20] |
Prohibitin/annexin 2 complex | S/VAT | [33] | |
Brown adipocytes | P2RX5 | BAT, CS/LC* | [20] |
PAT2 | BAT, CS/LC* | [20] | |
Adipocyte progenitor cells | Lin(−):Ter119(−)CD29(+):CD34(+):Sca-1(+):CD24(+) | S/VAT | [24] |
iBAT | [26] | ||
PDGFRα(+):Lin(−):CD29(+):CD34(+):Sca-1(+):CD24(+) | SAT | [25] | |
PDGFRα(+):CD34(+):Sca-1(+):CD24(−):PDGFRβ(−) | VAT | [27] | |
Lin(−):CD34(+):CD38(+) | S/VAT, iBAT | [29] | |
Zfp423(+):CD45(−):CD29(+)Sca-1(+):CD24(−) | SAT | [30] | |
Zfp423(+):CD45(−):CD29(+)Sca-1(−):CD24(+/−) | VAT | ||
PDGFRα(+):PDGFRβ(−) | SAT | [31] | |
PDGFRα(+):PDGFRβ(−), PDGFRα(−):PDGFRβ(−) | VAT | ||
Lin(−):Gp38(+):PDGFRα(+):CD9(low) | VAT | [34] | |
Lin(−):CD34(+):CD44(+):PDGFRα(+):CD9(low) | VAT* | ||
Lin(−):Ly6c(−):CD9(−):PDGFRβ(+) | VAT | [35] | |
Lin(−):Ter119(−):Sca-1(+):CD55(high) | VAT | [36] | |
Lin(−):Ter119(−):Sca-1(+):CD29(+):CD34(+):CD142(−) | S/VAT, SAT* | [37] | |
Lin(−):CD26/DPP4(+):CD142(−) | S/VAT, SAT* | [38] | |
Lin(−):CD34(+):CD44(+):ΔDecorin(+) | WAT | [39] | |
Preadipocytes | PDGFRα(+):Lin(−):CD29(+):CD34(+):Sca-1(+):CD24(−) | SAT | [25] |
PDGFRα(+):PDGFRβ(−), PDGFRα(+):PDGFRβ(+) | SAT | [31] | |
PDGFRα(+):PDGFRβ(−), PDGFRα(−):PDGFRβ(+) | VAT | ||
Lin(−):PDGFRβ (+):Zfp423(+) | S/VAT | [32] | |
Lin(−):Ter119(−):Sca-1(+):CD55(low) | VAT | [36] | |
Lin(−):CD54/ICAM1(+):CD142(−) | S/VAT, iBAT | [38] | |
Endothelial cells | Prohibitin | S/VAT, WAT* | [40] |
SAT, subcutaneous white adipose tissue; VAT, visceral white adipose tissue; iBAT, interscapular brown adipose tissue; CS, carotid sheath; LC, longus colli; Lin, CD45 and CD31; *, Human samples; WAT, white adipose tissue.