Table 12.
Proposed statements | Level of agreement |
N | Consensus achieved | ||
---|---|---|---|---|---|
Disagree (%) | Equivocal (%) | Agree (%) | |||
1. Pseudo-progression has not been demonstrated in urothelial cancer | 0 | 11 | 89 | 28 | Yes |
2. In contrast to the first-line setting, the PD-L1 biomarker is not useful for selecting patients for immunotherapy in platinum-refractory metastatic urothelial cancer | 4 | 15 | 81 | 28 | Yes |
3. Carboplatin-based chemotherapy remains a viable first-line treatment option in cisplatin-ineligible, PD-L1-positive patients with metastatic urothelial carcinoma until data from randomised phase III trials of ICIs are available | 3 | 10 | 87 | 29 | Yes |
4. Cisplatin-ineligible, immunotherapy-refractory patients with metastatic urothelial carcinoma should be considered for chemotherapy instead of sequencing of immunotherapy | 7 | 12 | 81 | 27 | Yes |
Statements highlighted in green achieved consensus.
ICI, immune checkpoint inhibitor; N, number of voters; PD-L1, programmed death-ligand 1.