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. 2020 Jan 8;30(11):1697–1727. doi: 10.1093/annonc/mdz296

Table 12.

Consensus meeting statements regarding ICIs in urothelial bladder cancer

Proposed statements Level of agreement
N Consensus achieved
Disagree (%) Equivocal (%) Agree (%)
1. Pseudo-progression has not been demonstrated in urothelial cancer 0 11 89 28 Yes
2. In contrast to the first-line setting, the PD-L1 biomarker is not useful for selecting patients for immunotherapy in platinum-refractory metastatic urothelial cancer 4 15 81 28 Yes
3. Carboplatin-based chemotherapy remains a viable first-line treatment option in cisplatin-ineligible, PD-L1-positive patients with metastatic urothelial carcinoma until data from randomised phase III trials of ICIs are available 3 10 87 29 Yes
4. Cisplatin-ineligible, immunotherapy-refractory patients with metastatic urothelial carcinoma should be considered for chemotherapy instead of sequencing of immunotherapy 7 12 81 27 Yes

Statements highlighted in green achieved consensus.

ICI, immune checkpoint inhibitor; N, number of voters; PD-L1, programmed death-ligand 1.