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. Author manuscript; available in PMC: 2021 Jun 4.
Published in final edited form as: J Membr Biol. 2020 Jun 4;253(3):287–298. doi: 10.1007/s00232-020-00124-3

Figure 2. PG-1 induced leakage of anionic bilayers.

Figure 2.

The leakage of ANTS/DPX probes encapsulated in 50POPG:50POPC LUV was measured before and after the addition of PG-1. The kinetics of the leakage event were dependent on [peptide], with samples containing 1:200 peptide:lipid ratios showing a fast saturation at ~60% leakage. The reduced state of the peptide, controlled by the addition of 2-mercapthoethanol (ME) indicated in orange, did not affect leakage kinetics.