Table 4.

Correlation Between Sleep Apnea Variables and Pancreatic β-Cell Function

Variables	Normal Glucose Tolerance					Prediabetes
	HOMA-IR	HOMA-β	ΔI30/ΔG30	AUC-I180	DIO	HOMA-IR	HOMA-β	ΔI30/ΔG30	AUC-I180	DIO
AHI (rp, P value)	0.004, 0.944	−0.011, 0.862	−0.086, 0.155	0.053, 0.384	0.030, 0.618	0.112, 0.178	−0.083, 0.318	−0.037, 0.662	−0.141, 0.091	−0.113, 0.177
ODI (rp, P value)	0.062, 0.336	0.045, 0.486	−0.099, 0.120	0.083, 0.196	0.005, 0.937	0.106, 0.239	−0.132, 0.139	−0.105, 0.242	−0.129, 0.150	−0.215, 0.016
Mean SpO2 (rp, P value)	−0.184, 0.025	−0.181, 0.027	0.035, 0.673	−0.118, 0.152	0.146, 0.076	−0.173, 0.116	0.062, 0.573	0.068, 0.538	0.109, 0.325	0.302, 0.005
LSpO2 (rp, P value)	−0.120, 0.060	−0.087, 0.172	0.070, 0.275	−0.116, 0.068	0.045, 0.487	−0.013, 0.880	0.096, 0.279	0.105, 0.240	0.127, 0.152	0.058, 0.515
TS90 (rp, P value)	0.120, 0.055	0.034, 0.586	−0.114, 0.069	0.032, 0.614	0.001, 0.986	−0.060, 0.487	−0.114, 0.186	−0.508, 0.502	−0.170, 0.048	−0.159, 0.064

Notes: Data are provided as partial correlation coefficient (r_p) using partial correlation analysis with adjustment for age and sex.

Abbreviations: BMI, body mass index; AHI, apnea-hypopnea index; ODI, oxygen desaturation index; Mean SpO₂, mean pulse oxygen saturation; LSpO₂, lowest pulse oxygen saturation; TS90, percent of total sleep time spent below 90% oxygen saturation; HOMA-IR, homeostasis model assessment–insulin resistance; HOMA-β, homeostasis model assessment-β; ΔI₃₀/ΔG₃₀, the early phase (0 min−30 min) insulinogenic index; AUC-I₁₈₀, total area under the curve of insulin in 180 minutes; DI_O, oral disposition index.