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. 2020 Jul 10;15:1643–1654. doi: 10.2147/COPD.S253567

Table 1.

Pharmacological Costs of the Triple Therapy (MITT)

Combination Market Share Daily Cost, €
LABA/ICS + LAMA Trade name % group: 81% Individual Weighted
Salmeterol/fluticasone Seretide 39.9% 1.376 2.80
Formoterol/budesonide Symbicort 20.5% 1.542
Beclometasone/formoterol Fostair 23.8% 1.589
Vilanterol/fluticasone Relvar 15.8% 1.589
Tiotropium Spiriva 100.0% 1.308
LAMA/LABA + ICS % group: 19% Individual Weighted
Indacaterol/glycopyrronium Ultibro 44.7% 2.652 3.02
Olodaterol/tiotropium Spiolto 32.9% 2.513
Umeclidinium/vilanterol Anoro 5.6% 2.166
Aclidinium/formoterol Duaklir 16.8% 2.166
Budesonide Pulmicort 100.0% 0.526
Weighted daily cost for MITT 2.84

Notes: Source: Market share33 and Daily cost.36

Abbreviations: ICS, inhaled corticosteroid; LABA, long-acting beta-agonist; LAMA, long-acting muscarinic antagonist; MITT, multiple-inhaler triple therapy.