Table 7.

Summary of pmrB and pmrA Mutations Reported in Col^R E. coli

Bacteria/Strain/Source	Observed Mutations	Reference
E. coli O25 (human clinical specimens)	Deletion ∆27-45 LISVFWLWHESTEQIQLFE; pmrB	[53]
E. coli O25 and O18 (human clinical specimens)	G206D; pmrB	[53]
E. coli O25 (human clinical specimens)	L105P; pmrA	[53]
E. coli LC711/14 (urinary tract infected human patient)	L10P; pmrB	[48]
E. coli (human clinical specimens)	A118T, E123D, Y315F, and Y358N; pmrB	[54]
E. coli (Parisian fecal samples)	L10P, L10R, C84R, C84Y, P94A, P94L, P94Q, E121K, E121Q, A159P, and A159V; pmrB G53A, G53C, G53E, G53R, G53S, G53V, G53W, R81L, and R81S; pmrA	[57]
E. coli (swine)	S138N, E123D, T156A, G160E, V161G, and V351I; pmrB G144S, S39I, and R81S; pmrA	[55,56]
E. coli (calf cecum samples)	D283G and Y358N; pmrB	[58]
E. coli (poultry farms)	P94L and D283G; pmrB S29G; pmrA	[59]