Table 2.
Patients: tumor volumes were estimated in triplicate in a total of 32 MRI scans with each of three different methods.
| Parameter | Osirix | ITK-SNAP | BrainLab |
|---|---|---|---|
| Patient 1 | |||
| MRI #1 | |||
| Mean estimated volume (ml) | 3.77 | 4.52 | 3.51 |
| Standard deviation (ml) | 0.09 | 0.13 | 0.02 |
| Coefficient of variation | 0.02 | 0.03 | 0.01 |
| MRI #2 | |||
| Mean estimated volume (ml) | 3.96 | 4.40 | 3.63 |
| Standard deviation (ml) | 0.02 | 0.06 | 0.02 |
| Coefficient of variation | 0.00 | 0.01 | 0.01 |
| MRI #3 | |||
| Mean estimated volume (ml) | 3.97 | 4.34 | 3.71 |
| Standard deviation (ml) | 0.04 | 0.12 | 0.13 |
| Coefficient of variation | 0.01 | 0.03 | 0.03 |
| MRI #4 | |||
| Mean estimated volume (ml) | 4.07 | 4.42 | 4.00 |
| Standard deviation (ml) | 0.04 | 0.07 | 0.13 |
| Coefficient of Variation | 0.01 | 0.02 | 0.03 |
| Patient 2 | |||
| MRI #1 | |||
| Mean estimated volume (ml) | 5.80 | 6.67 | 5.16 |
| Standard deviation (ml) | 0.04 | 0.03 | 0.10 |
| Coefficient of variation | 0.01 | 0.00 | 0.02 |
| MRI #2 | |||
| Mean estimated volume (ml) | 6.38 | 6.80 | 5.54 |
| Standard deviation (ml) | 0.07 | 0.12 | 0.02 |
| Coefficient of variation | 0.01 | 0.02 | 0.00 |
| MRI #3 | |||
| Mean estimated volume (ml) | 6.62 | 6.61 | 5.36 |
| Standard deviation (ml) | 0.08 | 0.20 | 0.01 |
| Coefficient of Variation | 0.01 | 0.03 | 0.00 |
| MRI #4 | |||
| Mean estimated volume (ml) | 6.46 | 6.61 | 6.46 |
| Standard deviation (ml) | 0.23 | 0.07 | 0.06 |
| Coefficient of variation | 0.04 | 0.01 | 0.01 |
| Patient 3 | |||
| MRI #1 | |||
| Mean estimated volume (ml) | 3.09 | 3.50 | 3.17 |
| Standard deviation (ml) | 0.07 | 0.13 | 0.04 |
| Coefficient of variation | 0.02 | 0.04 | 0.01 |
| MRI #2 | |||
| Mean estimated volume (ml) | 3.73 | 3.44 | 2.75 |
| Standard deviation (ml) | 0.06 | 0.07 | 0.06 |
| Coefficient of variation | 0.02 | 0.02 | 0.02 |
| MRI #3 | |||
| Mean estimated volume (ml) | 3.64 | 3.68 | 3.03 |
| Standard deviation (ml) | 0.11 | 0.13 | 0.06 |
| Coefficient of variation | 0.03 | 0.03 | 0.02 |
| MRI #4 | |||
| Mean estimated volume (ml) | 3.58 | 3.69 | 2.90 |
| Standard deviation (ml) | 0.02 | 0.02 | 0.02 |
| Coefficient of variation | 0.01 | 0.00 | 0.01 |
| Patient 4 | |||
| MRI #1 | |||
| Mean estimated volume (ml) | 8.39 | 8.86 | 7.90 |
| Standard deviation (ml) | 0.06 | 0.24 | 0.02 |
| Coefficient of variation | 0.01 | 0.03 | 0.00 |
| MRI #2 | |||
| Mean estimated volume (ml) | 9.03 | 9.18 | 8.35 |
| Standard deviation (ml) | 0.11 | 0.03 | 0.06 |
| Coefficient of variation | 0.012 | 0.00 | 0.01 |
| MRI #3 | |||
| Mean estimated volume (ml) | 13.16 | 13.61 | 12.35 |
| Standard deviation (ml) | 0.14 | 0.32 | 0.18 |
| Coefficient of variation | 0.011 | 0.023 | 0.015 |
| MRI #4 | |||
| Mean estimated volume (ml) | 11.64 | 11.42 | 10.52 |
| Standard deviation (ml) | 0.12 | 0.13 | 0.32 |
| Coefficient of variation | 0.01 | 0.01 | 0.03 |
| Patient 5 | |||
| MRI #1 | |||
| Mean estimated volume (ml) | 0.53 | 0.57 | 0.40 |
| Standard Deviation (ml) | 0.00 | 0.02 | 0.01 |
| Coefficient of Variation | 0.00 | 0.03 | 0.03 |
| MRI #2 | |||
| Mean estimated volume (ml) | 0.57 | 0.50 | 0.49 |
| Standard deviation (ml) | 0.01 | 0.02 | 0.01 |
| Coefficient of variation | 0.01 | 0.04 | 0.02 |
| MRI #3 | |||
| Mean estimated volume (ml) | 0.57 | 0.58 | 0.50 |
| Standard deviation (ml) | 0.01 | 0.03 | 0.01 |
| Coefficient of variation | 0.01 | 0.05 | 0.02 |
| MRI #4 | |||
| Mean estimated volume (ml) | 0.55 | 0.54 | 0.47 |
| Standard deviation (ml) | 0.01 | 0.05 | 0.01 |
| Coefficient of variation | 0.01 | 0.09 | 0.02 |
| Patient 6 | |||
| MRI #1 | |||
| Mean estimated volume (ml) | 0.42 | 0.68 | 0.49 |
| Standard deviation (ml) | 0.01 | 0.04 | 0.02 |
| Coefficient of variation | 0.02 | 0.06 | 0.05 |
| MRI #2 | |||
| Mean estimated volume (ml) | 0.44 | 0.70 | 0.53 |
| Standard deviation (ml) | 0.00 | 0.01 | 0.03 |
| Coefficient of variation | 0.01 | 0.02 | 0.05 |
| MRI #3 | |||
| Mean estimated volume (ml) | 0.46 | 0.68 | 0.56 |
| Standard deviation (ml) | 0.02 | 0.03 | 0.04 |
| Coefficient of variation | 0.03 | 0.04 | 0.08 |
| MRI #4 | |||
| Mean estimated volume (ml) | 0.48 | 0.69 | 0.60 |
| Standard deviation (ml) | 0.01 | 0.02 | 0.02 |
| Coefficient of variation | 0.02 | 0.03 | 0.03 |
| Patient 7 | |||
| MRI #1 | |||
| Mean estimated volume (ml) | 0.22 | 0.45 | 0.28 |
| Standard deviation (ml) | 0.01 | 0.03 | 0.01 |
| Coefficient of variation | 0.03 | 0.06 | 0.05 |
| MRI #2 | |||
| Mean estimated volume (ml) | 0.24 | 0.50 | 0.27 |
| Standard deviation (ml) | 0.01 | 0.00 | 0.01 |
| Coefficient of variation | 0.04 | 0.00 | 0.04 |
| MRI #3 | |||
| Mean estimated volume (ml) | 0.27 | 0.50 | 0.30 |
| Standard deviation (ml) | 0.02 | 0.04 | 0.01 |
| Coefficient of Variation | 0.09 | 0.07 | 0.01 |
| MRI #4 | |||
| Mean estimated volume (ml) | 0.28 | 0.49 | 0.32 |
| Standard deviation (ml) | 0.01 | 0.02 | 0.00 |
| Coefficient of variation | 0.02 | 0.04 | 0.02 |
| Patient 8 | |||
| MRI #1 | |||
| Mean estimated volume (mll) | 0.14 | 0.31 | 0.22 |
| Standard deviation (ml) | 0.00 | 0.01 | 0.02 |
| Coefficient of variation | 0.03 | 0.04 | 0.08 |
| MRI #2 | |||
| Mean estimated volume (ml) | 0.13 | 0.30 | 0.27 |
| Standard deviation (ml) | 0.01 | 0.01 | 0.02 |
| Coefficient of variation | 0.09 | 0.03 | 0.08 |
| MRI #3 | |||
| Mean estimated volume (ml) | 0.13 | 0.33 | 0.27 |
| Standard deviation (ml) | 0.01 | 0.01 | 0.02 |
| Coefficient of variation | 0.04 | 0.02 | 0.06 |
| MRI #4 | |||
| Mean estimated volume (ml) | 0.10 | 0.34 | 0.28 |
| Standard deviation (ml) | 0.01 | 0.02 | 0.02 |
| Coefficient of variation | 0.08 | 0.06 | 0.08 |
We calculated the means, standard deviations (SD) and coefficients of variation (CV) of the three volume estimates at each time point for each patient using each method.