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. 2020 Jul 8;7:322. doi: 10.3389/fmed.2020.00322

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Copyright © 2020 Suárez-Méndez, Doval, Walter, Pasquín, Bernabé, Gallo, Valdés, Maestú, López-Sanz and Rodríguez-Mañas.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Seed-based functional connectivity analysis results for the right angular gyrus (rAG). The pink area represents the seed. The areas shaded in blue outline the clusters that are significantly hypoconnected to the rAG in frail individuals when compared to robust participants. The blue colormap indicates hyposynchronization in the frail group between the seed and the cluster. The blue colorbar represents the t-statistic values of each source of the significant cluster obtained by independent samples t-test. RH, right hemisphere; LH, left hemisphere; LS, lateral surface; MS, medial surface.