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. 2020 Jul 8;11:1550. doi: 10.3389/fmicb.2020.01550

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Copyright © 2020 Zhang, Gu, You, Xu, Zhou, Chen, Yan, Jiang, Li, Lv and Qian.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Alterations of gut microbiota in patients with primary immune thrombocytopenia (ITP) vs healthy controls (HCs). (A) Box plot of the Chao1 index, Shannon index and a two-dimensional plot of principal co-ordinates analysis built based on a bray matrix of the two groups. (B) Bacterial order, family, and genera enriched in feces of ITP patients. (C) Species enriched in ITP patients. (D) Phylum, genera and species depleted in ITP patients. The boxes represent the interquartile range, from the first and third quartiles, and the median is shown as a thick line in the middle of the box. The circles represent outliers beyond the whiskers. Each point in the graph represents a sample, and a color indicates a group of samples. p_ajust < 0.05 for all data selected.