Table 4.
Urinary biomarker levels in pre-renal and renal-type AKI patients based on the FENa criterion.
| Recovery | Proteinuria (mg/mg Cru) | Urinary NAG (IU/mg Cru) | Urinary NGAL (mg/mg Cru) | Urinary t-Gelsolin (AU/mg Cru) | Urinary KIM-1 (AU/mg Cru) | Urinary TCP1-eta (AU/mg Cru) | Urinary REG3A (AU/mg Cru) | Urinary FABP1 (AU/mg Cru) | Urinary GM2AP (AU/mg Cru) |
|---|---|---|---|---|---|---|---|---|---|
| Pre-renal AKI patients: biomarker data as a function of recovery from AKI | |||||||||
| Yes (n = 8) | 12.58 ± 2.47 | 24.37 ± 11.61 | 309.79 ± 136.34 | 0.08 ± 0.07 | 0.59 ± 0.19 | 4.75 ± 6.76 | 0.10 ± 0.10 | 0.02 ± 0.02 | 0.13 ± 0.05 |
| No (n = 7) | 12.80 ± 6.05 | 41.30 ± 13.05 | 193.62 ± 137.87 | 0.02 ± 0.01 | 0.20 ± 0.10 | 3.56 ± 5.08 | 0.15 ± 0.14 | 0.66 ± 0.64 | 0.16 ± 0.11 |
| Renal AKI patients: biomarker data as a function of recovery from AKI | |||||||||
| Yes (n = 32) | 11.14 ± 1.96 | 16.70 ± 5.57 | 524.78 ± 161.11 | 0.01 ± 0.01 | 0.38 ± 0.13 | 1.67 ± 2.64 | 0.09 ± 0.06 | 0.08 ± 0.03 | 0.14 ± 0.08 |
| No (n = 34) | 13.26 ± 2.20 | 18.51 ± 3.09 | 973.96 ± 172.96** | 0.08 ± 0.03** | 0.57 ± 0.13 | 2.83 ± 2.73* | 0.15 ± 0.04 | 0.26 ± 0.10 | 0.25 ± 0.07*** |
Data are expressed as the mean ± SEM.
AU: arbitrary units; Crp: plasma creatinine; Cru: urinary creatinine; FABP1: fatty acid binding protein 1; GM2AP: GM2-activator protein; KIM-1: kidney injury molecule 1; NAG: N-acetyl-β-d-glucosaminidase; NGAL: Neutrophil gelatinase-associated lipocalin; REG3A: regenerating islet-derived 3 alpha; RFI: renal failure index; TCP1-eta: T-complex protein 1 eta.
*p < 0.05 **p < 0.01 ***p < 0.001 versus “Recovery: Yes” group.