Figure 12.
Comparison of transcriptomic changes in PBMCs induced by M04, LPS, and cGAMP. (A) Volcano plots illustrating −log10(p value) and fold change of significantly differentially regulated transcripts for indicated stimulus relative to cells exposed to DMSO vehicle treatment. Gene symbols of the top 15 transcripts as determined by Manhattan distance are labeled; (B) Venn diagram illustrating patterns of similarity in indicated stimulus-specific upregulated transcripts; (C) Fold change correlation of all detected transcripts between indicated stimuli. Pearson correlation coefficient (r) presented for each comparison.