TABLE 1.
Baseline Patient Characteristics
| Characteristic | Short-survival group N = 40 | Long-survival group N = 213 | Total N = 253 | P value |
|---|---|---|---|---|
| Age at surgery/radiotherapy (years) | .957b | |||
| Mean (SD) | 57.6 (12.1) | 57.5 (11.1) | 57.5 (11.2) | |
| Gender, n (%) | 40 | 213 | 253 | <.001c |
| Female | 9 (22.5) | 119 (55.9) | 128 (50.6) | |
| Male | 31 (77.5) | 94 (44.1) | 125 (49.4) | |
| ECOG classification, n (%) | 40 | 211 | 251 | .038d |
| 0-Fully active | 0 (0.0) | 24 (11.4) | 24 (9.6) | |
| 1-Restricted in physically strenuous activity but ambulatory and able to carry out work of light or sedentary nature | 14 (35.0) | 89 (42.2) | 103 (41.0) | |
| 2-Ambulatory and capable of all self-care but unable to carry out any work activities. Up and about more than 50% of waking hours | 12 (30.0) | 55 (26.1) | 67 (26.7) | |
| 3-Capable of only limited self-care | 10 (25.0) | 33 (15.6) | 43 (17.1) | |
| 4-Completely disabled. Cannot carry on any self-care. Totally confined to bed or chair | 4 (10.0) | 10 (4.7) | 14 (5.6) | |
| 5-Dead | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
| Site of the primary cancer, n (%) | 40 | 213 | 253 | <.001c |
| Breast | 0 (0.0) | 46 (21.6) | 46 (18.2) | |
| Lungs | 16 (40.0) | 34 (16.0) | 50 (19.8) | |
| Prostate | 1 (2.5) | 14 (6.6) | 15 (5.9) | |
| Kidney | 3 (7.5) | 37 (17.4) | 40 (15.8) | |
| Other | 20 (50.0) | 82 (38.5) | 102 (40.3) | |
| The original primary cancer site remains controlled, n (%) | 37 | 211 | 248 | .560c |
| No | 15 (40.5) | 75 (35.5) | 90 (36.3) | |
| Yes | 22 (59.5) | 136 (64.5) | 158 (63.7) | |
| Time since primary tumor diagnosis (months) | .161e | |||
| Mean (SD) | 28.5 (41.9) | 41.0 (50.0) | 39.0 (48.9) | |
| Other site(s) of metastases, n (%)a | 40 | 213 | 253 | |
| None | 9 (22.5) | 84 (39.4) | 93 (36.8) | |
| Brain | 6 (15.0) | 10 (4.7) | 16 (6.3) | |
| Visceral | 20 (50.0) | 70 (32.9) | 90 (35.6) | |
| Axial skeletal metastases (spine/pelvis) | 15 (37.5) | 69 (32.4) | 84 (33.2) | |
| Appendicular skeletal metastases | 5 (12.5) | 30 (14.1) | 35 (13.8) | |
| Other | 6 (15.0) | 30 (14.1) | 36 (14.2) | |
| Pain, n (%)a | 40 | 213 | 253 | |
| None | 1 (2.5) | 7 (3.3) | 8 (3.2) | |
| Axial pain | 34 (85.0) | 165 (77.5) | 199 (78.7) | |
| Radicular pain | 17 (42.5) | 104 (48.8) | 121 (47.8) | |
| Type of axial pain, n (%)a | 34 | 165 | 199 | |
| Mechanical | 23 (67.6) | 131 (79.4) | 154 (77.4) | |
| Biological | 20 (58.8) | 62 (37.6) | 82 (41.2) | |
| Epidural compression for most severe compression (re-grouped), n (%) | 40 | 205 | 245 | .001c |
| Bilsky 0-1c | 11 (27.5) | 113 (55.1) | 124 (50.6) | |
| Bilsky 2-3 | 29 (72.5) | 92 (44.9) | 121 (49.4) | |
| AIS at baseline, n (%) | 40 | 213 | 253 | <.001d |
| A | 1 (2.5) | 0 (0.0) | 1 (0.4) | |
| B | 3 (7.5) | 2 (0.9) | 5 (2.0) | |
| C | 6 (15.0) | 8 (3.8) | 14 (5.5) | |
| D | 12 (30.0) | 60 (28.2) | 72 (28.5) | |
| E | 18 (45.0) | 143 (67.1) | 161 (63.6) | |
| Total SINS score | .101b | |||
| n | 40 | 212 | 252 | |
| Mean (SD) | 11.2 (3.0) | 10.3 (3.2) | 10.4 (3.2) |
aMultiple answer options possible.
b t-test.
cChi-square test.
dFisher's exact test.
eWilcoxon rank-sum test.