TABLE 2.
MICs of antibiotics and ethidium bromide for S. Typhimurium and A. baumannii strains at the indicated concentrations of auranofina
| Strain and Afn concn (μΜ) | MIC (μg/ml) |
|||
|---|---|---|---|---|
| Chl | Nal | Tet | EtBr | |
| S. Typhimurium SL1344 ramR::aph | ||||
| 0 | 16 | 8 | 4 | 512 |
| 6 | 16 | 8 | 1 | 256 |
| 13 | 16 | 4 | 1 | 128 |
| 25 | 16 | 4 | 0.5 | 64 |
| 50 | 0.06 | 0.015 | 8 | |
| A. baumannii AB211 | ||||
| 0 | 128 | 512 | >2,048 | 128 |
| 6 | 16 | 32 | 4 | 32 |
| 13 | 1 | 2 | 2 | |
a
Chl, chloramphenicol; Nal, nalidixic acid; Tet, tetracycline; EtBr, ethidium bromide; Afn, auranofin. Bold font indicates synergy, as determined by an FIC index value of <0.5.