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. 2020 Jun 3;39(14):e103812. doi: 10.15252/embj.2019103812

Figure EV4. HFD‐dependent alterations in lipid storages and species (related to Figs 3 and 4).

Figure EV4

  • A
    Weight gained (g/15 days) and mouse body weight following the administration of HFD in wt (black bars and traces, n = 10) and LowOXPHOS (orange bars and traces, n = 10) mice.
  • B
    Food intake (g HFD/mouse/day) in wt (n = 5) and LowOXPHOS (n = 4) animals. No differences were observed.
  • C
    Representative images of v‐WAT in wt and LowOXPHOS mice and total lipids (nmol/mg tissue) in v‐WAT from wt (n = 8) and LowOXPHOS (n = 8) animals.
  • D, E
    Heat maps of the quantitative lipidomics for TAGs and DAGs species in Skm from wt (n = 8) and LowOXPHOS (n = 8) mice. The color scale (yellow to blue) in the heat map represents the z‐score.
  • F, G
    WAT saturated DAG (nmol/mg tissue, F) and Skm number of saturated lipid species (G); wt, n = 8; LowOXPHOS, n = 8.
Data information: Data are the mean ± SEM of indicated (n) mice; *P < 0.05 when compared to wt by Student's t‐test.