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. 2020 Mar 22;75(7):576–583. doi: 10.1136/thoraxjnl-2018-213021

Figure 2.

Figure 2

Inclusion of different analytes into eight proteins for the diagnosis of TB disease. (A) Overall importance index of the proteins in the eight-protein biosignature to the RF model, where a higher number reflects higher importance. (B) AUC values obtained from receiver operator characteristic curve analysis of each of the proteins in the eight-protein biosignature distinguishing definite TB (n=53) from non-TB (n=252), HC (n=84), LTBI (n=84) and PN (n=84), respectively. FAP, fibroblast activation protein; HC, healthy control; I-TAC, interferon-inducible T-cell alpha chemoattractant (also called CXLC11); I-309, also called CCL1/TCA3; LTBI, latent tuberculosis infection; LYVE-1, lymphatic vessel endothelial hyaluronan receptor 1; MEP1B, meprin A subunit beta; MIG, monokine induced by gamma interferon (also called CXCL9); PN, pneumonia; RF, random forest algorithm