Table 2.

Definitions used in classifying study participants

Classification	Definition
HC	Negative CXR, no clinical symptoms of tuberculosis, no history of TB, negative IGRAs
LTBI	Negative CXR, no clinical symptoms of tuberculosis, no history of TB, positive IGRAs
PN	Negative cultures for MTB, negative smears, radiographic suggestive of non-PTB and no history of TB
Definite TB	Sputum culture-positive for MTB plus CT suggestive of PTB; or positive smears plus symptoms responding to TB treatment, CT suggestive of PTB
Probable TB	No sputum or negative smear and negative MTB, but CT evidence and symptoms responding to TB treatment

CXR, chest X-ray; HC, healthy control; LTBI, latent tuberculosis infection; MTB, Mycobacterium tuberculosis; PN, pneumonia; PTB, pulmonary tuberculosis.