Table 3.
Variables in the multivariable predictive regression model of radiological pathology in multidrug-resistant tuberculosis with rate ratios and their associated lower and upper 95% CI, SE and p values
| Variable | Rate ratio | Upper CI | Lower CI | SE | P value* |
| Mutation | |||||
| katG.315 | 1.14 | 1.28 | 1.01 | 0.07 | 1.00 |
| rpoB.450 | 0.81 | 0.94 | 0.69 | 0.06 | 0.03 |
| rpoC.1040 | 1.97 | 2.16 | 1.77 | 0.10 | <0.01 |
| rpoB.435 | 1.21 | 1.40 | 1.01 | 0.10 | 1.00 |
| Rv2828c.141 | 1.30 | 1.39 | 1.21 | 0.04 | <0.01 |
| embB.306 | 0.86 | 0.97 | 0.74 | 0.06 | 0.27 |
| rpoB.445 | 1.09 | 1.25 | 0.93 | 0.08 | 1.00 |
| Male gender | 1.13 | 1.23 | 1.04 | 0.05 | 0.29 |
| HIV positive | 0.84 | 1.02 | 0.66 | 0.09 | 1.00 |
| Age 10–19 | Comparison | Comparison | Comparison | Comparison | Comparison |
| Age 20–29 | 0.97 | 1.08 | 0.87 | 0.05 | 1.00 |
| Age 30–39 | 0.66 | 0.82 | 0.50 | 0.08 | <0.01 |
| Age 40–49 | 0.93 | 1.08 | 0.78 | 0.08 | 1.00 |
| Age 50–59 | 1.20 | 1.37 | 1.02 | 0.09 | 1.00 |
| Age 60–69 | 0.71 | 1.04 | 0.38 | 0.17 | 1.00 |
| Age 70–79 | 0.43 | 0.79 | 0.07 | 0.18 | <0.01 |
| MDR | Comparison | Comparison | Comparison | Comparison | Comparison |
| Mono-resistant | 0.86 | 0.99 | 0.72 | 0.07 | 0.75 |
| Previous TB | 1.19 | 1.28 | 1.10 | 0.05 | <0.01 |
| Lineage 2 | Comparison | Comparison | Comparison | Comparison | Comparison |
| Lineage 4 | 1.28 | 1.49 | 1.08 | 0.10 | 0.48 |
| Lineage 4.1.1 | 1.32 | 1.54 | 1.10 | 0.11 | 0.33 |
| Lineage 4.1.1.3 | 1.06 | 1.34 | 0.78 | 0.14 | 1.00 |
| Lineage 4.1.2.1 | 1.34 | 1.52 | 1.16 | 0.09 | 0.05 |
| Lineage 4.3.2 | 1.15 | 1.40 | 0.89 | 0.13 | 1.00 |
| Lineage 4.3.3 | 1.02 | 1.18 | 0.87 | 0.08 | 1.00 |
| Lineage 4.3.4.1 | 0.61 | 0.89 | 0.33 | 0.14 | 0.02 |
| Lineage 4.3.4.2 | 1.26 | 1.43 | 1.08 | 0.09 | 0.27 |
| Lineage 4.8 | 0.98 | 1.39 | 0.57 | 0.21 | 1.00 |
*Bonferroni-corrected p value.