Table 3.

Top 10 biological processes altered in septic lungs treated with MSCs

Biological processes	FDR	Combined score
Torso signalling pathway (GO:0008293)	0.0004	36.33
Positive regulation of transcription from RNA polymerase II promoter (GO:0045944)	0.0119	32.39
Integrin-mediated signalling (GO:0007229)	0.0023	31.64
Regulation of transcription involved in cell fate commitment (GO:0060850)	0.0009	30.26
Regulation of transcription in anterior/posterior axis specification (GO:0044324)	0.0012	29.08
Positive regulation of transcription from RNA polymerase III promoter (GO:0045945)	0.0042	28.45
Regulation of transcription from RNA polymerase II promoter (GO:0060994)	0.0015	28.35
Regulation of SREBP signalling pathway (GO:2000638)	0.0015	28.27
Regulation of transcription from RNA polymerase II promoter (GO:1901213)	0.0027	27.78
Positive regulation of DNA-templated transcription, elongation (GO:0032786)	0.0045	27.7

FDR, false discovery rate; GO, gene ontology; MSC, mesenchymal stromal cell.