Table 3.

Inhibitory effect of remdesivir-diltiazem combined treatment against SARS-CoV-2 in vitro. For each experimental condition, IC50, CC50 and the corresponding SI values are listed.

Combination treatment	IC50 ($\mu$M)	CC50 ($\mu$M)	SI
Remdesivir	0.987	275	278.62
Remdesivir + Diltiazem 5.62 $\mu$M	0.627	267	425.83
Remdesivir + Diltiazem 11.5 $\mu$M	0.116		2301.72
Remdesivir + Diltiazem 22.5 $\mu$M	0.228		1171.05
Diltiazem	>45	424	<9.42
Diltiazem + Remdesivir 0.625 $\mu$M	5.268	414	78.59
Diltiazem + Remdesivir 1.25 $\mu$M	1.892		218.81
Diltiazem + Remdesivir 2.5 $\mu$M	0.554		747.29