Figure 7. holo‐MICOS complex assembly induces remodeling of the mitochondrial inner membrane.

• A
  FIB‐SEM of Mic10‐TO cells. Cells were induced for 0, 16, and 24 h. The representative reconstructions show mitochondria from noninduced, rescued, and intermediate cells, as indicated. The OM is shown together with the IBM in clear gray, the CM in blue.
• B
  ET of Mic10‐TO cells. Mic10 expression was induced for 0 and 16 h. Shown are reconstructions of representative noninduced and almost completely rescued mitochondria. The OM is displayed in clear gray; the side of the IM that faces the matrix is shown in dark blue. The IM side that faces the IMS is shown in light blue.

Data information: Scale bars: 500 nm.