Table 1.
Patient characteristics
| Patient | Medical history | Clinical examination | Biology | SARS‐CoV‐2 PCR | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Age/Sex | Relevant past medical history | Associated viral symptoms | Time between 1st symptoms and consultation (days) | Skin symptoms duration to healing (days) | Clinical description | Topography | Antinuclear antibodies (titre) | SARS‐CoV‐2 serological status | Nasopharyngeal swab | Skin biopsy | |
| 1 | 60/F | Raynaud's disease | None | 28 | 38 | Purplish macule | Right index fingertip | Negative | Negative | / | Negative |
| 2 | 32/H | / | Asthenia | 25 | 35 | Erythematous and purplish patches and papules with superficial erosion | Dorsal side of the toes (right I, III, IV, V and left I, II, IV, V) | Negative | Negative | Negative | Negative |
| 3 | 11/H | / | Asthenia, headaches | 28 | 27 | Erythematous purplish patches and papules with superficial erosion and post‐inflammatory scaling | Dorsal surface of the toes (both side I and II) | Negative | Negative | / | Negative |
| 4 | 18/H | / | None | 16 | 27 | Erythematous, livedoid and purplish patches and papules with superficial erosion | Dorsal and lateral sides of the toes (left I, II, III, V) and fingers |
Positive (1/640) anti‐centromere antibodies |
Negative | Negative | Negative |
| 5 | 34/F | Raynaud's disease, chilblains | None | 52 | >60 | Purplish and livedoid macules with post‐inflammatory scaling | Dorsal side and fingertips of the all toes |
Positive (1/2560) nucleolar fluorescence |
/ | Negative | Negative |
| 6 | 57/F | / | None | 14 | >60 | Purplish macules | All fingertips |
Positive (1/160) dense cytoplasmic fluorescence |
Negative | / | Negative |
| 7 | 24/H | / | None | 22 | 29 | Erythematous and purplish patches and papules with superficial erosion and post‐inflammatory scaling | Dorsal side of the toes (right III, IV, V and left II, IV, V) | Negative | Negative | Negative | / |
| 8 | 50/F | / | Asthenia | 37 | 45 | Purplish and livedoid patches | Toe fingertips (left I, II, III) | Negative | Negative | Negative | Negative |
| 9 | 40/F | Raynaud's disease, chilblains | Headaches | 24 | >60 | Erythematous patches with post‐inflammatory scaling | Dorsal side of the fingers with respect of the interphalangeal joints ( right II, III, IV, V and left II, III, IV, V) | Negative | Negative | Negative | Negative |
| 10 | 14/H | / | Cough, asthenia, headaches, myalgia, arthralgia | 35 | 43 | Erythematous, liveoid and purplish purplish patches and papules with post‐inflammatory pigmentation and scaling | Dorsal surface and fingertips of all toes | Negative | Negative | Negative | Negative |