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. 2020 Aug 28;5:24. Originally published 2020 Feb 10. [Version 2] doi: 10.12688/wellcomeopenres.15651.2

Table 4. Statistical differences between guests and cohort participants.

Table showing statistical comparisons. Mann-Whitney U-tests were used to compare the opinions of cohort members and guests.Results have not been adjusted for multiple comparisons. There is no indication that failure to answer one question had any impact on the next, so each question has been analysed individually. Cohort groups have been compared using Kruskal Wallis tests. Where the results were significant post-hoc pairwise comparisons were performed using Dunn's test and the Bonferroni correction for multiple tests applied. Significant results are highlighted in yellow and labelled. The number of people who answered each question is also listed. There are many reasons why people may not have answered a particular question including practical factors like arriving late or leaving early, or failing to press a button within the allocated 10 seconds. In addition, some people have been excluded from this analysis, because they did not answer question 1, therefore we cannot allocate them to the categories of ‘cohort member’ or ‘guest’.

Comparing Cohort members to guests Comparing Cohort
Groups
Question No. Cohort
Members
No. of
Guests
Total
(n)
Mann-
Whitney
U
Significance
(p)
Notes Kruskal
Wallis
(H)
Degrees
of
freedom
Significance
(p)
Post-hoc pairwise
comparisons (Dunn's
test adjusted for
multiple comparisons)
1.Which
cohort/guest
2. Age of
consent
129 60 189 3346 0.121 7.322 3 0.062
3. Pregnant
Women
135 64 199 4111 0.518 12.246 3 0.007 ACONF more positive
than LBC (p=0.020)
4. Blood spots 135 64 199 4102 0.413 11.206 3 0.011 ACONF more positive
than Gen Scot (p=0.047)
5. Access
health record
134 63 197 3738 0.081 4.987 3 0.173
6. Fitbit 133 62 195 3888 0.427 4.697 3 0.195
7. Trust
researchers
133 64 197 3349 0.008 Cohort members
more trusting than
guests
4.328 3 0.228
8. Trust
doctors
135 63 198 3110 0.001 Cohort members
more trusting than
guests
8.823 3 0.032 No statistically significant
results
9. Trust
companies
134 61 195 3499 0.095 4.049 3 0.256
10. Brain scan
for research
128 56 184 3279 0.319 3.366 2 186
11. Brain scan
for health info
128 57 185 3256 0.209 1.224 2 0.542
12. Invite
children/
grandchildren
125 56 181 3460 0.825 2.322 2 0.313
13.
Reapproach
re: post-
mortem brain
donation
121 51 172 2291 0.005 Cohort members
more positive than
guests
0.172 2 0.917
14. Repeat
testing more
regularly
121 40 161 1886 0.015 Cohort members
more positive than
guests.
5.239 2 0.073
15. Change
lifestyle
125 46 171 2530 0.205 10.647 2 0.005 ACONF more positive
than LBC (p=0.007)
16. Take new
drug
122 47 169 2757 0.687 1.429 2 0.489