TABLE 3.
Laboratory findings on admission and clinical outcomes of COVID‐19 patients
| Parameters | Aggravated (N = 17) | Nonaggravated (N = 54) | P value |
|---|---|---|---|
| Coagulation function test | |||
| FIB (g/L; normal range 2.00‐4.00) | 3.84 (3.51‐4.40) | 3.96 (3.42‐4.17) | .532 |
| Increased | 8 (47.1) | 19 (35.2) | .379 |
| APTT (s; normal range 20.00‐40.00) | 30.40 (24.30‐34.65) | 26.10 (24.10‐28.43) | .027 |
| Increased | 0 (0.0) | 0 (0.0) | >.99 |
| PT (s; normal range 9.00‐13.00) | 12.00 (11.75‐12.80) | 11.50 (10.90‐11.83) | <.001 |
| Increased | 3 (17.6) | 3 (5.6) | .144 |
| TT (s; normal range 14.00‐21.00) | 17.20 (16.95‐19.35) | 18.10 (17.30‐19.00) | .200 |
| INR (normal range 0.70‐1.30) | 1.07 (1.05‐1.14) | 1.02 (0.96‐1.05) | <.001 |
| Increased | 1 (5.9) | 0 (0.0) | .239 |
| FDP (mg/L; normal range 0.0‐5.0) | 13.00 (5.50‐65.05) | 2.40 (1.70‐5.00) | <.001 |
| Increased | 14 (82.4) | 13 (24.1) | <.001 |
| D‐D (mg/L; normal range 0.00‐0.55) | 5.95 (1.23‐20.08) | 0.44 (0.25‐1.19) | <.001 |
| Increased | 15 (88.2) | 18 (33.3) | <.001 |
| AT (%; normal range 75.0‐141.0) | 76.10 (63.40‐81.35) | 84.25 (79.48‐91.95) | <.001 |
| Decreased | 7 (41.2) | 5 (9.3) | .007 |
| Liver function test | |||
| ALT (U/L; normal range 7‐45) | 25.00 (15.50‐112.00) | 24.50 (13.75‐40.00) | .217 |
| Increased | 7 (41.1) | 12 (22.2) | .220 |
| AST (U/L; normal range 13‐35) | 38.00 (24.50‐88.50) | 23.00 (17.75‐35.00) | .003 |
| Increased | 9 (52.9) | 12 (22.2) | .016 |
| TBiL (μmol/L; normal range 2.0‐24.0) | 14.30 (11.45‐18.55) | 11.30 (8.58‐15.03) | .036 |
| Increased | 2 (11.8) | 3 (5.6) | .587 |
| DBiL (μmol/L; normal range 0.0‐7.0) | 2.80 (1.30‐4.45) | 1.50 (1.08‐2.35) | .026 |
| Increased | 1 (5.9) | 1 (1.9) | .424 |
| Diagnostic enzyme index | |||
| LDH (U/L; normal range 114‐250) | 382.00 (271.00‐515.00) | 180.00 (157.00‐218.00) | <.001 |
| Increased | 14 (82.4) | 6 (11.1) | <.001 |
| CRP (mg/L; normal range 0.00‐5.00) | 73.20 (31.50‐128.00) | 3.11 (3.11‐12.45) | <.001 |
| Increased | 16 (94.1) | 19 (35.2) | <.001 |
Data are median (IQR) or n (%).P values comparing patients in the aggravated group and in the nonaggravated group are from Chi‐square test, Fisher's exact test, or Mann‐Whitney U test.
Aggravated, patients in the aggravated group; Nonaggravated, patients in the nonaggravated group.
Abbreviations: ALT, alanine aminotransferase; APTT, activated partial thromboplastin time; AST, aspartate aminotransferase; AT, antithrombin; CRP, C‐reactive protein; DBiL, direct bilirubin; D‐D, D‐Dimers; FDP, fibrin/fibrinogen degradation products; FIB, fibrinogen; INR, international normalized ratio; LDH, lactate dehydrogenase; PT, prothrombin time; TBiL, total bilirubin; TT, thrombin time.