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. 2020 Jul 22;111(9):3379–3385. doi: 10.1111/cas.14544

TABLE 2.

Immune state of 6 hematological patients and duration of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection

Clinical outcome Circulating immune cell subsets a Anti‐SARS‐CoV‐2 Abs (normal value < 10 AU/mL) Duration of SARS‐CoV‐2 infection (d) b Total course in hospital (d) c
B cells (/μL) T cells (/μL) IgM (AU/mL) IgG (AU/mL) Detection time point (day after illness onset)
CD4+ T cells CD8+ T cells
Alive Case 2 46 66 101 16.53 65.08 32 48+ 48+
Case 3 41 719 284 0.94 1.42 33 48+ 48
Case 5 ND ND ND 1.76 0.76 18 45+ 23
Case 6 ND ND ND 7.31 2.74 21 53+ 27
Case 8 1 257 234 1.37 1.26 38 19 52
Dead Case 9 0 37 119 0.48 2.97 23 23 23

Abbreviation: Abs, antibodies; ddPCR, droplet digital PCR; ND, not done.

a

Normal range of circulating immune cell subsets: B cells, 90‐560/μL; helper T cells, 550‐1440/μL; suppressor/cytotoxic T cells, 320‐1250/μL.

b

Determination of plasma nucleic acid of SARS‐CoV‐2 in cases 3, 5, and 6 by One‐step RT‐ddPCR, SARS‐CoV‐2 infection as confirmed by the positive result of a throat swab test in cases 2 and 8. +, SARS‐CoV‐2 infection continued.

c

+, Case 2 is still in hospital.