Figure 1.

Three-dimensional printed Si-HPMC constructs with microchannels. (A) Design of the first of the odd layers of the construct, where darker line represents gelatin printed strands, and lighter lines represent Si-HPMC strands. (B) Design of even layers of the construct. (C) Representation of the top view of the construct morphology of the 3D bioprinted construct of cell-laden Si-HPMC. Printed constructs with microchannels (D) before and (E) after gelatin removal (9 × 9 × 4 mm). (F) Representation of a cross section of the channeled construct (without bottom and top Si-HPMC-only layers). (G) Optical image of the transversal slice of the stained construct exhibiting microchannels after gelatin removal. (H) A zoomed-in part of the transversal slice. Si-HPMC: silanized hydroxypropylmethylcellulose.