Table 2.
Summary table of the diagnostic accuracy of IgG, IgM, and IgG/IgM for SARS‐CoV‐2 infection
| Sensitivity (95% CI) | Specificity (95% CI) | DOR (95% CI) | LRpos (95% CI) | LRneg (95% CI) | AUC (95% CI) | |
|---|---|---|---|---|---|---|
| IgG | 0.85 (0.79‐0.90) | 0.99 (0.98‐1.00) | 592.62 (226.79‐1634.34) | 88.32 (38.48‐229.57) | 0.15 (0.10‐0.22 | 0.99 (0.97‐0.99) |
| IgM | 0.74 (0.65‐0.81) | 0.99 (0.97‐1.00) | 278.12 (76.02‐1029.37) | 71.41 (22.09‐259.48) | 0.27 (0.18‐0.36) | 0.95 (0.93‐0.97) |
| IgG/IgM | 0.86 (0.79‐0.92) | 0.99 (0.97‐1.00) | 777.53 (161.26‐3478.47) | 104.14 (24.99‐456.71) | 0.14 (0.08‐0.22) | 0.98 (0.96‐0.99) |
Abbreviations: AUC, area under the curve; CI, confidence interval; DOR, diagnostic odds ratio; IgG, immunoglobulin G; IgM, immunoglobulin M; LRpos, positive likelihood ratio; LRneg, negative‐positive likelihood ratio.