Table 1.
Baseline demographic, clinical, and treatment characteristics of patients
| Variable | Patient 1 | Patient 2 |
|---|---|---|
| Age, y | 51 | 63 |
| Sex | M | M |
| BMI, kg/m2 | 22 | 18 |
| Race | AA | AA |
| Symptoms at presentation | ||
| Fever | No | No |
| Dyspnea | Yes | Yes |
| Cough | No | Yes |
| Nausea/emesis | Yes | No |
| Myalgias | Yes | No |
| Vital signs baseline (peak) | ||
| Temp | 98.8 (100.8) | 98.3 (98.7) |
| RR, per min | 17 (25) | 17 (20) |
| HR, per min | 66 (99) | 94 (110) |
| Oxygen Saturation | 86 (85) | 90 (90) |
| SBP, mm Hg | 153 (180) | 130 (143) |
| Baseline (peak) lab. values | ||
| WBC, ×109/L | 5.1 (11) | 2.4 (5.7) |
| Lymphocytes, ×109/L | 18 | 34 (49) |
| Hemoglobin, g/dL | 12.7 (12.9) | 12.8 (13) |
| Platelets, ×109/L | 88 (155) | 454 (459) |
| AST, units/L | 108 (131) | 53 |
| ALT, units/L | 78 (84) | 43 |
| ALP, IU/L | 135 (135) | 92 |
| BUN, mg/dL | 11 (24) | 33 |
| Creatinine, mg/dL | 0.8 (0.9) | 1.6 |
| CRP, mg/L | … | 4.95 (4.95) |
| ESR, h | … | 131 (131) |
| Ferritin, ng/mL | 742 (1264) | 2292 (2292) |
| Superimposed infection | Streptococcus pneumoniae | None |
| HAART regimen | None | None |
| Immunological profile | ||
| CD4 cell count | 10.2 | 116.3 |
| HIV RNA PCR copies | 26 900 | 2 540 000 |
| Management | ||
| Hydroxychloroquine | NA | NA |
| Corticosteroids | NA | NA |
| Tocilizumab | NA | NA |
| Antibiotics | Azithromycin, bactrim, zosyn | Bactrim |
| Other | … | Zinc sulfate, vitamin C |
| Outcomes | ||
| Length of hospitalization, d | 10 | 7 |
| ICU admission, n (%) | 0 (0) | 0 (0) |
| Mechanical ventilation, n (%) | 0 (0) | 0 (0) |
| In‐hospital death, n (%) | 0 (0) | 0 (0) |
| Readmission | 0 (0) | 0 (0) |
Abbreviations: ALP, alkaline phosphatase; ALT, alanine transaminase; AST, aspartate transaminase; BMI, Body mass index; BUN, blood urea nitrogen; CD4, cluster of differentiation 4; CRP, C reactive protein; HAART, highly active antiretroviral therapy; HIV RNA PCR, human immunodeficiency virus ribonucleic acid polymerase chain reaction; HR, heart rate; ICU, intensive care unit; RR, respiratory rate; SBP, systolic blood pressure; SR, erythrocyte sedimentation rate; WBC, white blood cell count.