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. 2020 Jun 4;12(6):1290. doi: 10.3390/polym12061290

Table 1.

(a) Thickness (mm) analysis of the three experimental membranes (Derma Fina, Evolution Standard and Duo-Teck) after immersions periods up to 21 days in PBS (Hydrolytic degradation test), collagenase from Clostridium histolyticum (Bacterial collagenase resistance test) and trypsin (Enzyme resistance test). Values shown are mean and standard deviation. (b) Attained p values after pairwise comparisons between membranes’ thicknesses after the different immersion times and the initial thickness (thickness at t0: Th0). Significance was considered at p ≤ 0.001.

(a)
Derma Evolution Duo-Teck
Trypsin C. hystolyticum PBS Trypsin C. hystolyticum PBS Trypsin C. hystolyticum PBS
t0 1.02 (0.13) 1.09
(0.17)		 1.22 (0.04) 0.43 (0.14) 0.39
(0.05)		 0.47 (0.01) 0.15 (0.00) 0.15
(0.01)		 0.17 (0.00)
4 h 0.75 (0.05) 0.59
(0.05)		 0.85 (0.10) 0.21 (0.02) 0.14
(0.02)		 0.20 (0.03) 0.13 (0.04) 0.14
(0.01)		 0.18 (0.06)
8 h 0.64 (0.07) 0.54
(0.05)		 0.75 (0.08) 0.20 (0.06) 0.08
(0.01)		 0.23 (0.03) 0.11 (0.03) 0
(0)		 0.14 (0.05)
12 h 0.61 (0.06) 0.48
(0.07)		 0.66 (0.03) 0.16 (0.04) 0.06
(0.01)		 0.21 (0.04) 0.08 (0.01) 0
(0)		 0.11 (0.05)
16 h 0.60 (0.05) 0.41
(0.04)		 0.66 (0.05) 0.16 (0.04) 0.06
(0.01)		 0.20 (0.03) 0.07 (0.02) 0
(0)		 0.08 (0.02)
24 h 0.57 (0.02) 0.36
(0.03)		 0.63 (0.04) 0.08 (0.02) 0.05
(0.01)		 0.16 (0.06) 0.04 (0.04) 0
(0)		 0.09 (0.01)
48 h 0.51 (0.04) 0.34
(0.02)		 0.63 (0.03) 0.06 (0.03) 0.05
(0.01)		 0.13 (0.01) 0.03 (0.03) 0
(0)		 0
(0)
72 h 0.49 (0.05) 0.28
(0.03)		 0.60 (0.05) 0.03 (0.02) 0.03
(0.01)		 0.10 (0.03) 0.01 (0.02) 0
(0)		 0
(0)
7 d 0.49 (0.02) 0.20
(0.05)		 0.59 (0.03) 0.03 (0.03) 0
(0)		 0.05 (0.03) 0.01 (0.01) 0
(0)		 0
(0)
14 d 0.53 (0.07) 0.08
(0.04)		 0.56 (0.04) 0.04 (0.03) 0
(0)		 0.04 (0.02) 0
(0)		 0
(0)		 0
(0)
21 d 0.57 (0.07) 0
(0)		 0.52 (0.08) 0.04 (0.03) 0
(0)		 0.05 (0.01) 0
(0)		 0
(0)		 0
(0)
(b)
Th0-Th1 0.002 <0.001 <0.001 0.008 <0.001 <0.001 0.152 0.602 0.323
Th0-Th4h 0.001 <0.001 <0.001 0.002 <0.001 <0.001 0.009 <0.001 0.46
Th0- Th8h <0.001 <0.001 <0.001 0.002 <0.001 <0.001 0.02 <0.001 0.052
Th0-Th12h <0.001 <0.001 <0.001 0.001 <0.001 <0.001 0.035 <0.001 <0.001
Th0-Th16h <0.001 <0.001 <0.001 0.001 <0.001 <0.001 0.001 <0.001 <0.001
Th0-Th24h <0.001 <0.001 <0.001 0.001 <0.001 <0.001 <0.001 <0.001 <0.001
Th0-Th48h <0.001 <0.001 <0.001 0.001 <0.001 <0.001 <0.001 <0.001 <0.001
Th0- Th72h <0.001 <0.001 <0.001 0.001 <0.001 <0.001 <0.001 <0.001 <0.001
Th0-Th7d <0.001 <0.001 <0.001 0.001 <0.001 <0.001 <0.001 <0.001 <0.001
Th0-Th14d <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001
Th0-Th21d <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001