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. 2020 Jul 17;92(11):2792–2803. doi: 10.1002/jmv.26212

Figure 4.

Figure 4

A, Multiple sequence alignment (MSA) results of the receptor‐binding domain (RBD) (319th‐541st aa) (top row) of severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) (accession# YP_009724390) and the RBD of S protein (306th‐527th aa) of SARS‐CoV‐1 (accession# NP_828851) showed 73.09% of sequence identities. Note five (red stars) of the six amino acid residues mutated in (top row) in RBD of SARS‐CoV‐2. B, Except for the motif, segments of transmembrane regions and points of mutagenesis were noted in between the S protein of and SARS‐CoV‐2 (top row) and of SARS‐CoV‐1 (bottom row)