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. 2020 Jul 17;92(11):2792–2803. doi: 10.1002/jmv.26212

Figure 5.

Figure 5

Homology modeling results of receptor‐binding domain (RBD) of severe acute respiratory syndrome coronavirus‐1 (SARS‐CoV‐1) and SARS‐CoV‐2. A, The results for SARS‐CoV‐2 RBD (319th‐541st aa) showed a template‐based model of perfusion structure of RBD of S protein of SARS‐CoV‐1. B, On homology modeling, the RBD of SARS‐CoV‐1 (306th‐527th aa) developed a template‐based model of SARS‐CoV‐2 RBD (brown ribbons) in complex with ACE2 (green ribbons) with PDB ID (6vw.1). C, The sequence of RBD of SARS‐CoV‐2 aligned with the template (5b5x chain A, B, C) sequences show the near‐identical amino acid similarities between the B and C chains of the template and the Seqres S protein (top row) (template‐based models were developed by SWISS‐MODEL automated and accessible at the database: https://swissmodel.expasy.org/templates/6vw1.1 and PDB ID at https://www.rcsb.org/3d-view/6VW1/1)