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Design and synthesis of fluorinated probe. (a) Structure of polymer and nanogel. (i) Nanogel formation via crosslinking of PDS groups with DTT (ii) Cleavage of THP group in the presence of HCl and formation of negatively charged moiety with NaOH addition. (b) Schematic representation of preparation of fluorinated nanogel with decreased interior density. Reproduced from [242] with permission from American Chemical Society, 2019.
