Table 1.
Total | No DSPN | Minimal DSPN | Subclinical DSPN | DSPN | |
---|---|---|---|---|---|
Patient no. | 145 | 64 | 19 | 18 | 44 |
mMNSI, mean ± SD total score | 2.7 ± 0.7 | 1 ± 1 | 4 ± 0∗∗∗ | 2 ± 1 | 5 ± 1∗∗∗ |
DPNP, n (%) | 16 (11.0) | 5 (7.8) | 0 (0.0) | 1 (5.6) | 10 (22.7)∗ |
Abbreviations: mMNSI: modified Michigan Neuropathy Screening Instrument; DSPN: distal symmetrical polyneuropathy; DPNP: diabetic peripheral neuropathic pain; NCS: nerve conduction studies; DN4: Douleur Neuropathique; SD: standard deviations. aDPNP indicates patients with DN4≧4. bNo DSPN, patients with mMNSI total score < 2.5 and NCS severity score 0-1; minimal DSPN, patients with mMNSI total score≧2.5 and NCS severity score 0-1; subclinical DSPN, patients with mMNSI total score < 2.5 and NCS severity score≧2; DSPN, patients with mMNSI total score≧2.5 and NCS severity score≧2. Data were compared by DSPN stage against no DSPN, using the two-sample t-test for the mMNSI total score and the chi-squared test for the DPNP rate. ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.0001 indicate significant difference as compared with no DSPN.