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A) Representation of the saxitoxin biosynthetic gene cluster from Microseira wollei. Genes in purple, dark blue, and green indicate enzymes that have been characterized for roles in paralytic shellfish toxin biosynthesis, and light blue indicates the enzyme SxtG. B) Reaction performed by polyketide-like synthase SxtA. C) Proposed role of SxtG to operate on the SxtA product and downstream reactions toward saxitoxin.
