Table 4.
Thirty-day outcome data of initial operative versus conservative management with separate analyses for operative management versus antibiotics and interventional radiology drain placement and operative management versus antibiotics alone
| Event/Total (%) | Total (n = 470) |
Operative management (n = 219) | Initial conservative management (n = 251) |
|||
|---|---|---|---|---|---|---|
| Antibiotics and IR drain (n = 251) | P value | Antibiotics alone (n = 244) | P value | |||
| Collection* | 27/470 (6) | 19/219 (8) | 8/251 (4) | 0.01 | 5/244 (2) | 0.001 |
| Collection requiring IR drain | 3/470 (1) | 0/219 (0) | 3/251 (1) | 0.252 | 0/244 (0) | |
| Collection requiring re-operation | 6/470 (1) | 5/219 (2) | 1/251 (0) | 0.102 | 0/244 (0) | |
| Ileus** | 14/470 (4) | 14/219 (8) | 0/251 (0) | < 0.001 | 0/244 (0) | < 0.001 |
| Wound infection*** | ||||||
| Antibiotics | 18/470 (3) | 16/219 (7) | 2/251 (1) | < 0.001 | 2/242 (0.8) | < 0.001 |
| Wound Opened | 9/470 (2) | 8/219 (4) | 1/251 (1) | 0.014 | 1/244 (0.4) | 0.02 |
| Hospital Acquired Pneumonia | ||||||
| Oral Antibiotics | 1/470 (0.2) | 1/219 (0.5) | 0/251 (0) | 1 | 0/244 (0) | 0.47 |
| IV Antibiotics | 6/470 (2) | 6/219 (3) | 0/251 (0) | 0.01 | 0/244 (0) | 0.01 |
| Deep Vein Thrombosis/ Pulmonary Embolism | 3/470 (0.2) | 1/219 (0.5) | 2/251 (1) | 1 | 2/244 (1) | 1 |
| Reoperation**** | 8/470 (2) | 7/219 (3) | 1/251 (0) | 0.03 | 0/244 (0) | 0.005 |
| Death | 0/470 (0) | 0/219 (0) | 0/251 (0) | 1 | 0/244 (0) | 1 |
| Unplanned level 2/3 care | 6/470 (2) | 5/219 (4) | 1/251 (0) | 0.1 | 1/243 (0.4) | 0.11 |
| Post presentation COVID | 7/470 (1) | 4/219 (2) | 3/251 (1) | 0.71 | 3/244 (1) | 0.71 |
| Failed conservative management | – | – | 26/251 (10) | – | 24/244 (9) | – |
Categorical data are presented as number/denominator (percentage); p values calculated by χ2 or Fisher’s exact test as appropriate
The bold typeset in the table highlights statistical significance
IR Interventional radiolog placement of, IV Intravenous
*Collection refers to an infected fluid collection or intra−abdominal abscess requiring treatment **Ileus was defined as a partial or complete non−mechanical blockade of the small intestine ***Wound infection includes both superficial and deep incisional surgical site infection, defined according to Center for Disease Control criteria as superficial “involving only skin and subcutaneous tissues” and deep as “involving deep structures such as fascia or muscle”.**** Reoperation is defined as a return to theatre