Table 1.
Summary of 32 articles included in systematic review and meta-analysis
| Source (first author) | Year | Most prevalent mutations | Sequencing or genotyping technique |
|---|---|---|---|
| Greiner et al32 | 2006 | TP53, ATM | Sanger sequencing |
| Fernàndez et al30 | 2010 | CCND1, IGH, TP53, ATM | PCR (or microarray) |
| Hartmann et al35 | 2010 | TP53 | PCR (or microarray) |
| Gualco et al33 | 2010 | CCND1, IGH | FISH (validated) |
| Halldórsdóttir et al34 | 2011 | TP53 | PCR (or microarray) |
| Kridel et al38 | 2012 | CCND1, NOTCH1 | Sanger sequencing |
| Navarro et al45 | 2012 | TP53, ATM, CDKN2A | PCR (or microarray) |
| Beà et al4 | 2013 | TP53, ATM, CCND1, IGH, KMT2D, NSD2 | WES, WGS, and targeted panel |
| Meissner et al43 | 2013 | TP53, ATM, CCND1, NOTCH1, IGH, UBR5, MEF2B, TRAF2 | NGS panel (18 genes) |
| Chapman-Fredricks et al26 | 2014 | TP53, ATM, CCND1, IGH | FISH (validated) |
| Rahal et al10 | 2014 | BIRC3, KMT2D, NOTCH1, TRAF2, UBR5 | NGS gene panel |
| Zhang et al50 | 2014 | TP53, ATM, CCND1, KMT2D, NOTCH1, COL16A1, SMARCA4, KMT2C | Sanger sequencing, WES, array |
| Chiron et al27 | 2014 | BTK | WES and targeted sequencing |
| Delfau-Larue et al29 | 2015 | TP53, ATM, MYC, CDKN2A, RB1 | FISH (validated) |
| Wu et al48 | 2016 | ATM, KMT2D, CARD11, MEF2B, CHSY3 | WES |
| Martin et al41 | 2016 | BTK | WES and targeted panel |
| Eskelund et al9 | 2017 | TP53, ATM, CCND1, CDKN2A, BIRC3 | NGS panel (8 genes) |
| Hu et al36 | 2017 | CCND1, IGH | FISH (validated) |
| Zlamalikova et al51 | 2017 | TP53 | FISH (validated) |
| Khodadoust et al37 | 2017 | TP53, ATM, CCND1, UBR5, TTN | WES |
| Clot et al28 | 2018 | TP53, CDKN2A, IGH | Sanger sequencing, WES |
| Jain et al2 | 2018 | TP53, ATM, CCND1, CDKN2A, UBR5, NSD2, KRAS, FAT1 | NGS panel (300 genes) |
| Yang et al49 | 2018 | TP53, ATM, WHSC1 | WES |
| Obr et al46 | 2018 | TP53 | Sanger sequencing, WES, array |
| Lin et al39 | 2019 | TP53 | NGS gene panel |
| Agarwal et al3 | 2019 | TP53, ATM, BIRC3, IGH, WHSC1, SMARCA4, ARID1B, ARID1A | WES and NGS panel (42 genes) |
| Mori et al44 | 2019 | TP53, ATM, KMT2A | PCR (or microarray) |
| Zhang et al7 | 2019 | TP53, ATM, KMT2D, RB1, CCND1 | WES |
| Mareckova et al40 | 2019 | TP53, ATM | NGS panel (TP53 and ATM) |
| Martín-Garcia et al42 | 2019 | TP53, ATM, CCND2, CCND3 | WES, WGS, Sanger sequencing, FISH |
| Sakhdari et al47 | 2019 | TP53, ATM, CARD11 | NGS panel (29 and 53 genes) |
| Ferrero et al52 | 2019 | ATM, NSD2, KMT2D, CCND1, TP53, NOTCH1, BIRC3, TRAF2, KMT2D | NGS panel (9 genes) |