Table 1.
Clinical characteristics of the children
| Healthy controls (n = 22) | Mild febrile illness (n = 34) | UM (n = 50) | Nonmalarial coma (n = 10) | Ret−CM (n = 48) | Ret+CM (n = 170) | |
|---|---|---|---|---|---|---|
| Age, median (IQR), mo | 79 (43-107) | 41 (24-63) | 63 (40-92) | 46 (32-72) | 48 (28-69) | 47 (31-66) |
| Female sex, no. (%) | 9 (43) | 15 (44) | 26 (52) | 1 (10) | 23 (48) | 86 (51) |
| HIV positive, no. (%) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 4 (8.3) | 14 (8.2) |
| Axillary temperature, median (IQR), °C | 36.8 (36.1-36.8) | 38.2 (37.9-38.6) | 38.3 (37.9-39.0) | 38.6 (38.4-39.0) | 38.7 (37.7-39.6) | 38.7 (38.9-39.6) |
| Pulse rate, median (IQR), beats per minute | 116 (102-124) | 136 (113-154) | 137 (119-147) | 140 (119-157) | 143 (130-164) | 150 (138-167) |
| Systolic BP, median (IQR), mmHg | 111 (103-118) | 117 (107-123) | 114 (107-122) | 100 (94-110) | 98 (90-105) | 95 (89-104) |
| Respiratory rate, median (IQR), breaths/min | 28 (20-32) | 32 (28-36) | 27 (24-32) | 37 (28-40) | 40 (36-52) | 44 (38-52) |
| Blood glucose, median (IQR), mmol/L | 5.2 (4.6-5.7) | 4.8 (4.4-5.4) | 5.8 (4.9-6.4) | 7.45 (6.2-8.8) | 6.7 (5.5-8.6) | 6.4 (5.3-8.0) |
| Blood lactate, median (IQR), mmol/L | 1.8 (1.8-2.00) | 1.7 (1.2-2.2) | 2.4 (1.9-3.0) | 3.1 (2.1-5.2) | 4.0 (2.9-7.1) | 6.5 (3.6-10.3) |
| Hb, median (IQR), g/L | 103 (98-111) | 115 (105-120) | 93 (76-107) | 91 (82-92) | 81 (68-100) | 64 (51-77) |
| Platelets, median (IQR), ×109/L | 402 (345-470) | 331 (239-388) | 132 (82-185) | 335 (176-462) | 138 (60-221) | 52 (28-84) |
| Peripheral parasite density, median (IQR), ×103/μL | 0 | 0 | 31 (0.7-32) | 0 | 48 (5-173) | 73 (15-273) |
Hb, hemoglobin; IQR, interquartile range.