Table 1.
Characteristics of study population by HTN
| No HTN | HTN | P value | |
|---|---|---|---|
| N | 25,298 | 18,293 | |
| Age, years | 55.41 (50.05–60.73) | 60.89 (55.38–68.15) | < 0.001 |
| BMI, kg/m2 | 23.46 (21.47–25.67) | 25.33 (23.23–27.64) | < 0.001 |
| SBP, mmHg | 121.00 (112.00–130.00) | 149.00 (140.00–162.00) | < 0.001 |
| DBP, mmHg | 73.00 (68.00–79.00) | 85.00 (77.00–92.00) | < 0.001 |
| HR | 78.00 (71.00–86.00) | 79.00 (72.00–88.00) | < 0.001 |
| FBG, mmol/L | 5.40 (5.02–5.91) | 5.77 (5.29–6.58) | < 0.001 |
| PBG, mmol/L | 7.00 (5.81– 8.84) | 8.29 (6.60–11.24) | < 0.001 |
| HbA1c, % | 5.80 (5.60–6.20) | 6.00 (5.70–6.50) | < 0.001 |
| ALT, U/L | 14.00 (10.00–20.00) | 16.00 (12.00–22.00) | < 0.001 |
| AST, U/L | 20.00 (16.00–24.00) | 21.00 (17.00–25.00) | < 0.001 |
| GGT, U/L | 19.00 (14.00–28.00) | 23.00 (16.00–35.00) | < 0.001 |
| TG, mmol/L | 1.24 (0.90–1.79) | 1.52 (1.08–2.17) | < 0.001 |
| TC, mmol/L | 4.93 (4.21–5.68) | 5.14 (4.38–5.88) | < 0.001 |
| LDL-C, mmol/L | 2.84 (2.28–3.45) | 2.99 (2.40–3.61) | < 0.001 |
| HDL-C, mmol/L | 1.31 (1.09–1.55) | 1.25 (1.06–1.47) | < 0.001 |
| eGFR, mL/(min·1.73 m2) | 96.85 (93.10–100.56) | 92.98 (88.31–96.85) | < 0.001 |
| Sex, (%) | < 0.001 | ||
| Male | 6918 (27.35%) | 6201 (33.90%) | |
| Female | 18,380 (72.65%) | 12,092 (66.10%) | |
| Drinking, (%) | < 0.001 | ||
| Never | 18,643 (73.69%) | 14,023 (76.66%) | |
| Occasional | 5278 (20.86%) | 2883 (15.76%) | |
| Frequently | 1377 (5.44%) | 1387 (7.58%) | |
| Smoking, (%) | < 0.001 | ||
| Never | 21,443 (84.76%) | 15,779 (86.26%) | |
| Occasional | 862 (3.41%) | 495 (2.71%) | |
| Frequently | 2993 (11.83%) | 2019 (11.04%) | |
| CVDs, (%) | < 0.001 | ||
| Yes | 681 (2.69%) | 1690 (9.24%) | |
| No | 24,617 (97.31%) | 16,603 (90.76%) | |
| T2DM, (%) | < 0.001 | ||
| No | 22,723 (89.82%) | 14,226 (77.77%) | |
| Yes | 2575 (10.18%) | 4067 (22.23%) |
Data were mean ± SD or median (IQR) for skewed variables or numbers (proportions) for categorical variables
HTN hypertension, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HR heart rate, FBG fasting plasma glucose, PBG 2 h post-load blood glucose, HbA1c glycosylated hemoglobin, ALT alanine transferase, AST aspartate transferase, GGT gamma-glutamyl transferase, TG triglyceride, TC high cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, eGFR estimated glomerular filtration rate, CVD cardiovascular disease, T2DM type 2 diabetes