Table 1.
Characteristics of study design, inclusion criteria, population and baseline
| Study ID | Study design | Inclusion criteria | Sample size (I/C), male % | Mean age | Dropouts | Baseline depression score Mean (SD) | |
|---|---|---|---|---|---|---|---|
| Duarte (2009) [31] | RCT |
age:18-80 HD>3 months Mini International Neuropsychiatric Interview≥5 |
85 (41/44) Male: 35 (38.9%) |
I: (52.4±15.9), C: (54.0±12.7) |
5 I:5 |
BDI I: 24.2 (9.7) C: 27.3 (10.7) |
|
| Cukor (2014) [32] | RCT |
age>18 HD>6 months depression scale BDI-II >10 |
59 (33/26) Male: 16 (27%) |
Not reported |
6 Not reported the detailed dropout rates in each group |
BDI-II I: 24.7 (9.8) C: 21.9 (8.9) |
HAM-D I: 15.7 (6.8) C: 12.9 (5.3) |
| Lerma (2017) [30] | RCT |
age>18 HD>6 months BDI: mild or moderate scores |
49 (31/18) Male: 23 (47%) |
I: (41.8±14.7) C:(41.7±15.1) |
11 I:7 C:4 |
BDI I: 13.6 (7.6) C: 15.8 (10.0) |
|
| Valsara (2016) [33] | RCT |
age:20-65 HD>1 year HADS score>7 |
67 (33/34) Male: 47 (70.2%) |
66.67% in 43 to 65 years of age, | 13 |
HADS I: 11.85 (2.15) C: 11.21 (2.53) |
|
| Mehrotra (2019) [34] | RCT |
age≥21 HD ≥3 months BDI-II score≥15 |
114 (56/58) Male: 68 (57%) |
I: (50±13), C:(53±12) |
6 I:45 C:2 |
QIDS-C I: 12.2 (5.1) C: 10.9 (4.9) |
|
| Al saraireh (2018) [35] | RCT |
HD>1 year Hamilton depression rating scale |
105 (51/54) Male: 52 (50%) |
I: (53.4±8.0) C:(52±10.7) |
25 I: 11 C:14 |
HAM-D I: 19.5 (5.4) C: 19.6 (5.4) |
|
I intervention group, C comparison