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. 2020 Jul 14;20:369. doi: 10.1186/s12888-020-02754-2

Table 3.

Effect of intervention and control groups for HD on symptoms of depression and QoL at post-treatment and follow-up

Study ID Time-point Depression QoL
Measure Intervention Control MD/SMD (95% CI) Measure Intervention Control MD/SMD (95% CI)
Duarte (2009) [31] post-treatment BDI 14.1 (8.7) 21.2 (9.1) MD: -7.1 (-10.88, -3.32) KDQOL Only sub-dimensions scores of the scale were reported

follow-up

(6 mon)

10.8 (8.8) 17.6 (11.2) MD: -6.8 (-11.07, -2.53)
Cukor (2014) [32] post-treatment BDI-II 11.7 (9.8) 14.5 (8.5) MD: -2.8 (-7.47,1.87) KDQOL 115.3 (25.5) 110.6 (25.1) SMD: 0.18(-0.33,0.70)

follow-up

(3 mon)

9.9 (8.5) 9.1 (6.5) MD:0.8 (-3.03,4.63) 118.3 (27.7) 119.7 (24.7) SMD: -0.05(-0.57,0.46)
post-treatment HAM-D 6.5 (6.8) 10.9 (5.4) MD: -4.4 (-7.51, -1.29) - - - -

follow-up

(3 mon)

6.7 (5.8) 5.0 (4.3) MD:1.7 (-0.87,4.27) - - - -
Lerma (2017) [30] post-treatment BDI 10.2 (8.2) 15.0 (10.9) MD: -4.8 (-10.6,1.00) CIQOLP 109.6 (21.1) 94.0 (21.0) SMD: 0.73 (0.13,1.33)

follow-up

(1 mon)

7.1 (7.2) 14.7 (9.7) MD: -7.6 (-12.7, -2.45) 112.5 (23.8) 91.3 (22.5) SMD: 0.89 (0.28,1.50)
Valsara (2016) [33] post-treatment HADS 6.82 (1.86) 9.21 (2.69) MD: -2.39 (-3.49, -1.29) Not reported

follow-up

(3 mon)

6.73 (1.53) 9.74 (2.71) MD: -3.01 (-4.06, -1.96)
Mehrotra (2019) [34] post-treatment QIDS-C 8.1 (5.1) 5.9 (4.5) MD:2.2 (0.43,3.97) GQOL 5.6 (5.0 to 6.2) 6.4 (5.8 to 7.0) -
Al saraireh (2018) [35] post-treatment HADS 15.0 (5.5) 11.1 (2.3) MD:3.9 (2.27,5.52) Not reported