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. 2020 Jul 14;21:181. doi: 10.1186/s12931-020-01443-8

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Comparison of prevalence of microbiota clusters between controls and patients per age group. a nasal and b oropharyngeal microbiota clusters of controls and patients with any respiratory tract infection (RTI). c nasal and d oropharyngeal microbiota clusters of controls and patients with an upper respiratory tract infection (URTI). e nasal and f oropharyngeal microbiota clusters of controls and patients with a lower respiratory tract infection (LRTI). Act: Actinobacillus; Cor: Corynebacterium; Cut: Cutibacterium; Dol: Dolosigranulum; Ent: Enterobacteriaceae; Fus: Fusobacterium; Hae: Haemophilus; Lac: Lactobacillus; Mor: Moraxella; Nei: Neisseria; Pre: Prevotella; Rot: Rothia; Sta: Staphylococcus; Str: Streptococcus; Vei: Veillonella. Genera separated from each other by a comma are both represented in a relatively high abundance in each microbiota profile of the relevant cluster. Genera separated from each other by a slash indicates that one of these genera is present in a relatively high abundance. All P-values are based on Fisher’s Exact test. Correction for multiple testing was not performed