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. 2020 Jul 14;18:96. doi: 10.1186/s12951-020-00652-z

Fig. 2.

Fig. 2

The in vitro insulin release from GR-NPs in PBS buffer with different pH values (pH 1.2, 4.9, 6.8 and 8.0) (a); the residual insulin amount of GR-NPs in simulated gastric fluid (SGF) and simulated intestinal fluid (SIF) buffers (b), a significantly higher (**P < 0.01) efficacy of the residual insulin released form GR-NPs was observed at various time points in SIF/SGF compared with pure insulin