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pH changes (a), particle size changes (b) and UV330 absorbance (c) of GR-NPs under different glucose concentrations (0 mg/dL, 100 mg/dL and 400 mg/dL); morphology changes of GR-NPs in PBS and glucose solution (400 mg/dL) (d); mechanistic diagram of GR-NPs (e). A significantly higher (**P < 0.01, *P < 0.05) efficacy of GR-NPs was observed at various time points in 400 mg/dL compared with in PBS buffer
